Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–7 of 7 results
Advanced filters: Author: Maxence V Nachury Clear advanced filters

  • Cilia, and primary cilia in particular, are important signalling organelles with established roles in odorant, light and Hedgehog morphogen signal transduction. Cilia are enriched in signalling receptors and effectors and in specific lipids. Addressing how this unique composition is established and maintained is key to understanding cell signalling.

    • Maxence V. Nachury
    • David U. Mick
    Reviews
    Nature Reviews Molecular Cell Biology
    Volume: 20, P: 389-405

  • Experiments show that the progressive softening of microtubules under mechanical stress results from the enlargement of pre-existing structural defects, and that the incorporation of tubulin dimers can restore the microtubule’s initial stiffness.

    • Laura Schaedel
    • Karin John
    • Manuel Théry
    Research
    Nature Materials
    Volume: 14, P: 1156-1163

  • The BBSome is required for formation of primary cilia, sensory organelles whose dysfunction is linked to genetic disorders. Lorentzen and colleagues offer insight into BBSome membrane recruitment, providing a molecular rationale for common disease mutations.

    • André Mourão
    • Andrew R Nager
    • Esben Lorentzen
    Research
    Nature Structural & Molecular Biology
    Volume: 21, P: 1035-1041

  • Acetylation of α-tubulin on lysine 40 is associated with microtubule stability. In vitro experiments by Portran et al. show that tubulin acetylation reduces lateral interactions, increasing microtubule flexibility and resistance to mechanical stress.

    • Didier Portran
    • Laura Schaedel
    • Maxence V. Nachury
    Research
    Nature Cell Biology
    Volume: 19, P: 391-398

  • In eukaryotic cells, a subset of microtubules undergoes acetylation, resulting in stabilization: here, clathrin-coated pits are shown to control microtubule acetylation through a direct interaction between the α-tubulin acetyltransferase αTAT1 and the clathrin adaptor AP2, promoting directional cell migration.

    • Guillaume Montagnac
    • Vannary Meas-Yedid
    • Philippe Chavrier
    Research
    Nature
    Volume: 502, P: 567-570