High-resolution structures of large RNAs and protein–RNA complexes are difficult to solve due to inherent structural flexibility and a high risk of crystallization artefacts. Here, Duss et al. present a novel EPR-based approach to aid structure determination of large RNAs and protein–RNA complexes in solution.
- Olivier Duss
- Maxim Yulikov
- Frédéric H.-T. Allain
