Nature Search

Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Analyses of genome and exome sequencing data identify rare coding and structural variants associated with atrial fibrillation and highlight genetic links between atrial fibrillation and cardiomyopathies.

Seung Hoan Choi
Sean J. Jurgens
Patrick T. Ellinor
Research06 Mar 2025
Nature Genetics

Volume: 57, P: 548-562
Imposed work of breathing of 16 neonatal CPAP-devices using different mechanisms of CPAP generation

Hanna Sterzik
Joerg Arand
Bianca Haase
ResearchOpen Access25 Jul 2025
Pediatric Research

P: 1-6
Calculation of external climate costs for food highlights inadequate pricing of animal products

Agricultural greenhouse gas emissions not only amplify the global climate crisis, but cause damage currently unaccounted for by food prices. Here the authors show the calculation of prices with internalized climate costs for food categories and production systems, revealing strong market distortions.

Maximilian Pieper
Amelie Michalke
Tobias Gaugler
ResearchOpen Access15 Dec 2020
Nature Communications

Volume: 11, P: 1-13
The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes

The brushtail possum is a treasured Australian marsupial, but also a harmful pest introduced into New Zealand. Here, using functional genomics and a new chromosome-level genome assembly of New Zealand possums, Bond et al. quantify their genome admixture and identify unique parent-specific and weaning associated gene expression.

Donna M. Bond
Oscar Ortega-Recalde
Timothy A. Hore
ResearchOpen Access17 Oct 2023
Nature Communications

Volume: 14, P: 1-17
Towards complete and error-free genome assemblies of all vertebrate species

The Vertebrate Genome Project has used an optimized pipeline to generate high-quality genome assemblies for sixteen species (representing all major vertebrate classes), which have led to new biological insights.

Arang Rhie
Shane A. McCarthy
Erich D. Jarvis
ResearchOpen Access28 Apr 2021
Nature

Volume: 592, P: 737-746
Monitoring the binding and insertion of a single transmembrane protein by an insertase

The insertion and folding nascent or fully synthesized polypeptides into membranes is assisted by insertases. Here, the authors use a range of biophysical approaches to provide molecular details of how the transmembrane insertase YidC facilitates the insertion a protein into a phospholipid membrane.

Pawel R. Laskowski
Kristyna Pluhackova
Daniel J. Müller
ResearchOpen Access06 Dec 2021
Nature Communications

Volume: 12, P: 1-11
Large conformational changes of a highly dynamic pre-protein binding domain in SecA

Isabel Ernst et al. use single-molecule FRET measurements and in silico analyses to show the conformational changes of bacterial SecA. They show that the Preprotein Binding Domain is highly dynamic in the absence of ATP and moves toward the Helical Wing Domain when ATP is bound into the “wide open” position.

Isabel Ernst
Maximilian Haase
Sebastian Leptihn
ResearchOpen Access03 Sept 2018
Communications Biology

Volume: 1, P: 1-8
Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

Optimizing COVID-19 vaccination strategies for patients under immunosuppressive medication is of high importance. In this clinical trial including non-seroconverted immunosuppressed patients, a homologous mRNA booster vaccination resulted in higher seroconversion rate than a switch to a vector-based vaccine.

Daniel Mrak
Daniela Sieghart
Michael Bonelli
ResearchOpen Access12 Sept 2022
Nature Communications

Volume: 13, P: 1-9
Rational strain engineering in delafossite oxides for highly efficient hydrogen evolution catalysis in acidic media

The rational design of catalysts is crucial to make power-to-X technologies viable. Here the authors introduce the delafossite PdCoO₂ as a highly active hydrogen evolution reaction catalyst due to the growth of a tensile-strained Pd-rich capping layer under reductive conditions. Image credit: Christop Hohmann.

Filip Podjaski
Daniel Weber
Bettina V. Lotsch
Research23 Dec 2019
Nature Catalysis

Volume: 3, P: 55-63
Allogeneic stem cell transplantation in acute leukemia patients after COVID-19 infection

Maximilian Christopeit
Mirjam Reichard
Nicolaus Kröger
CorrespondenceOpen Access09 Feb 2021
Bone Marrow Transplantation

Volume: 56, P: 1478-1481

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