By pairing acoustic stimuli and electrical stimulation of the nucleus basalis neuromodulatory system in rats, the authors show an induction of long-lasting synaptic modifications of the auditory cortex that conserved excitation across the auditory receptive fields. This type of modification also improved auditory sensory detection and behavioral performance in tone perception.
- Robert C Froemke
- Ioana Carcea
- Christoph E Schreiner