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Showing 1–4 of 4 results
Advanced filters: Author: Meghan Riddell Clear advanced filters

  • Siglec-glycolipid interactions are often studied outside the context of a lipid bilayer. Here, the authors combine a variety of chemical biology techniques to demonstrate a unique and physiologically relevant ability of Siglec-6 to recognize glycolipids in a membrane.

    • Edward N. Schmidt
    • Dimitra Lamprinaki
    • Matthew S. Macauley
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17

  • While biallelic mutations of the SLC26A4 gene cause non-syndromic hearing loss with enlarged vestibular aqueducts or Pendred syndrome, a considerable number of patients carry mono-allelic mutations. Here the authors identify EPHA2 as another causative gene of Pendred syndrome with SLC26A4.

    • Mengnan Li
    • Shin-ya Nishio
    • Masanori Nakayama
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15

  • The cell polarity regulator aPKC is associated with cell proliferation but the precise mechanism are unknown. Here, the authors find that aPKC lambda phosphorylates the FoxO1 transcription factor, a gatekeeper of endothelial growth, during both angiogenesis and angiosarcomas.

    • Meghan Riddell
    • Akiko Nakayama
    • Masanori Nakayama
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-13

  • Older people have suboptimal responses to primary series vaccines, which can place them at risk for adverse coronavirus disease 2019 outcomes. Here the authors show that booster vaccines provide a substantial increase in antibody levels in the short term but that there is significant waning 100 d after booster shots.

    • Gokhan Tut
    • Tara Lancaster
    • Paul Moss
    ResearchOpen Access
    Nature Aging
    Volume: 3, P: 93-104