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Advanced filters: Author: Megumi Hosoya Clear advanced filters

  • Patients with higher total SVD scores were significantly more likely to have a stroke (A; P = 0.012) than those with lower total SVD scores. However, no association was observed between total SVD scores and acute coronary syndrome (B, P = 0.604). For incident stroke, total SVD scores of 1 and 2 were the cutoff levels.

    • Kazuo Kitagawa
    • Sono Toi
    • Hiroshi Yoshizawa
    Research
    Hypertension Research
    Volume: 47, P: 3001-3009

  • A total of 648 patients with any evidence of cerebral small vessel disease (SVD) in MRI and at least one vascular risk factor underwent Mini-mental State Examination (MMSE) and Japanese version of the Montreal Cognitive Assessment (MoCA-J) global cognitive tests. The total SVD scores count the presence of each SVD-related findings (white matter hyperintensity, Lacunar infarction, cerebral microbleeds and enlarged perivascular space), ranging from 0 to 4, as the SVD burden. Total SVD scores were significantly associated with MoCA-J scores (r = −0.203, P < 0.001). After adjustment for age, sex, education, risk factors, and medial temporal atrophy, the association between the total SVD score and global cognitive scores remained significant.

    • Megumi Hosoya
    • Sono Toi
    • Kazuo Kitagawa
    Research
    Hypertension Research
    Volume: 46, P: 1326-1334