Epidermal growth factor receptor (EGFR) elicits the signalling function after dimerization and activation of its kinase activity and perturbations in this pathway are often found in cancer. Here the authors describe two distinct and mutually exclusive modes of EGFR signalling due to a switch of EGFR-associated proteins with the ligand.
- Sharmistha Chakraborty
- Li Li
- Amyn A. Habib
