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Showing 1–2 of 2 results
Advanced filters: Author: Melissa Cadena Clear advanced filters

  • The response to infectious and inflammatory challenges differs among people but the reasons for this are poorly understood. Here the authors explore the impact of variables such as age, sex, and the capacity for controlling inflammation and maintaining immunocompetence, linking this capacity to favourable health outcomes and lifespan.

    • Sunil K. Ahuja
    • Muthu Saravanan Manoharan
    • Weijing He
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-31

  • The lack of effective drug delivery strategies has impaired the therapeutic progress in the treatment of glioblastoma (GBM). Here, the authors engineer synthetic protein nanoparticle based on polymerized human serum albumin equipped with the cell-penetrating peptide iRGD to deliver siRNA against STAT3 and report improved survival in a mouse model of GBM.

    • Jason V. Gregory
    • Padma Kadiyala
    • Joerg Lahann
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-15