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Showing 1–2 of 2 results
Advanced filters: Author: Melissa Wirawan Clear advanced filters

  • Dengue (DENV) and Zika (ZIKV) viruses normally display as smooth spherical particles, while DENV can also become bumpy-surfaced, resulting in immune evasion. Here, Morrone et al. report DENV and ZIKV infectious club-shaped particles (clubSP) that display distinct antibody binding properties.

    • Seamus R. Morrone
    • Valerie S. Y. Chew
    • Shee-Mei Lok
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • Temperature differences between mosquitoes and humans trigger structural changes in dengue virus 2 (DENV2) particles, but not in other DENV serotypes. Here, using HDXMS, the authors describe serotype-specific expansion of intact viral particles of DENV1 and DENV2 at 28 °C (mosquitoes), 37 °C (humans) and 40 °C (fever).

    • Xin-Xiang Lim
    • Arun Chandramohan
    • Ganesh S. Anand
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-13