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Early-onset colorectal cancer as an emerging disease of metabolic dysregulation

Cases of early-onset colorectal cancer (EOCRC) have risen alarmingly since the 1990s, alongside a surge in metabolic diseases, particularly obesity and type 2 diabetes mellitus (T2DM), among young populations. This Review synthesizes evidence regarding the association of obesity and T2DM with EOCRC.

Mengxi Du
David A. Drew
Andrew T. Chan
Reviews08 Aug 2025
Nature Reviews Endocrinology

Volume: 21, P: 686-702
Increasingly negative tropical water–interannual CO₂ growth rate coupling

Records show that tropical water availability rather than temperature appears to have been increasingly controlling the interannual variability of the terrestrial carbon cycle over the past 59 years.

Laibao Liu
Philippe Ciais
Sonia I. Seneviratne
ResearchOpen Access31 May 2023
Nature

Volume: 618, P: 755-760
A unified approach for divergent synthesis of contiguous stereodiads employing a small boronyl group

Predictable and unified approaches to all possible stereoisomers of acyclic compounds with contiguous stereocentres are rare. Here, the authors disclose a divergent α-functionalization of enolates with either syn or anti selectivity employing a β-boronyl group as a small, directing handle.

Miao Zhan
Zhengwei Ding
Pengfei Li
ResearchOpen Access07 Feb 2020
Nature Communications

Volume: 11, P: 1-9
The sex ratio of singleton and twin delivery offspring in assisted reproductive technology in China

Mengxi Chen
Jiangbo Du
Xiufeng Ling
ResearchOpen Access24 Aug 2017
Scientific Reports

Volume: 7, P: 1-8
The known genetic loci for telomere length may be involved in the modification of telomeres length after birth

Qiao Weng
Jiangbo Du
Hongbing Shen
ResearchOpen Access08 Dec 2016
Scientific Reports

Volume: 6, P: 1-7

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Early-onset colorectal cancer as an emerging disease of metabolic dysregulation

Increasingly negative tropical water–interannual CO2 growth rate coupling

A unified approach for divergent synthesis of contiguous stereodiads employing a small boronyl group

The sex ratio of singleton and twin delivery offspring in assisted reproductive technology in China

The known genetic loci for telomere length may be involved in the modification of telomeres length after birth

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Increasingly negative tropical water–interannual CO₂ growth rate coupling