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Nature Immunology (1)

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The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8⁺ T cells

The transcription factor BATF is required for differentiation of certain helper T cell subsets. Haining and colleagues show that BATF crucially regulates CD8⁺ effector cells by coordinating a transcription factor network.

Makoto Kurachi
R Anthony Barnitz
W Nicholas Haining
Research02 Mar 2014
Nature Immunology

Volume: 15, P: 373-383

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The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

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The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8⁺ T cells