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Showing 1–50 of 58 results

Advanced filters: Author: Michael A. Moskowitz Clear advanced filters

Univariate Genetic Analysis of Oxygen Transport Regulation in Children: The Medical College of Virginia Twin Study

William B Moskowitz
Michael Mosteller
Richard M Schieken
Research01 Jun 1993
Pediatric Research

Volume: 33, P: 645-648
Platelet-dependent stimulation of prostacyclin synthesis by platelet-derived growth factor

Shaun R. Coughlin
Michael A. Moskowitz
Lawrence Levine
Research11 Dec 1980
Nature

Volume: 288, P: 600-602
Treatment, toxicity, and mortality after subsequent breast cancer in female survivors of childhood cancer

Children receiving chest radiotherapy for childhood cancer have a higher risk of developing breast cancer later in life. Here, using the data from the Childhood Cancer Survivor Study, the authors investigate the treatment and survival outcomes of breast cancer patients who previously survived childhood cancer finding them to receive altered treatment and having increased mortality.

Cindy Im
Hasibul Hasan
Lucie M. Turcotte
ResearchOpen Access31 Mar 2025
Nature Communications

Volume: 16, P: 1-11
Author Correction: Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network

Mason E. Sweat
Yangpo Cao
William T. Pu
Amendments and Corrections31 Oct 2023
Nature Cardiovascular Research

Volume: 2, P: 1095
Dual site external validation of artificial intelligence-enabled treatment monitoring for neovascular age-related macular degeneration in England

Henry David Jeffry Hogg
S. James Talks
P. A. Keane
ResearchOpen Access19 Sept 2025
Eye

P: 1-7
Myocardial infarction accelerates atherosclerosis

Myocardial infarction accelerates atherosclerosis through activation of the sympathetic nervous system, and the consequent release of haematopoietic stem and progenitor cells.

Partha Dutta
Gabriel Courties
Matthias Nahrendorf
Research27 Jun 2012
Nature

Volume: 487, P: 325-329
Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

Ali Hafezi-Moghadam
Tommaso Simoncini
James K. Liao
Research01 May 2002
Nature Medicine

Volume: 8, P: 473-479
Platelet-derived growth factor is structurally related to the putative transforming protein p28^sis of simian sarcoma virus

Michael D. Waterfield
Geoffrey T. Scrace
Thomas F. Deuel
Research01 Jul 1983
Nature

Volume: 304, P: 35-39
Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis

This manuscript describes a new cerebral spinal fluid exit route via hundreds of skull channels, with the cranial bone marrow as a destination. In meningitis, bacteria hijack this path and alert hematopoietic stem cells residing in the skull marrow.

Fadi E. Pulous
Jean C. Cruz-Hernández
Matthias Nahrendorf
Research02 May 2022
Nature Neuroscience

Volume: 25, P: 567-576
Genetic Analysis of Anthropometric Measures in 11-Year-Old Twins: The Medical College of Virginia Twin Study

Joann N Bodurtha
Michael Mosteller
Richard M Schieken
Research01 Jul 1990
Pediatric Research

Volume: 28, P: 1-2
Stable transformation of maize after gene transfer by electroporation

Michael E. Fromm
Loverine P. Taylor
Virginia Walbot
Research27 Feb 1986
Nature

Volume: 319, P: 791-793
Differential localization of type I and type II benzodiazepine binding sites in substantia nigra

Mathew M. S. Lo
Debra L. Niehoff
Solomon H. Snyder
Research03 Nov 1983
Nature

Volume: 306, P: 57-60
Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial

In a phase 1b/2a trial, the combination of the oral PI3K inhibitor duvelisib and romidepsin had limited toxicity and exhibited encouraging clinical activity in patients with relapsed or refractory T cell lymphoma, suggesting an approach whereby PI3K inhibitors can be safely used in this patient population.

Steven M. Horwitz
Ajit J. Nirmal
Santosha A. Vardhana
Research17 Jun 2024
Nature Medicine

Volume: 30, P: 2517-2527
Correction: Corrigendum: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev
Zhihong Huang
Junying Yuan
Amendments and Corrections01 Sept 2005
Nature Chemical Biology

Volume: 1, P: 234
The 5-HT_1F receptor as the target of ditans in migraine — from bench to bedside

Ditans are a recently developed drug class for the treatment of acute migraine. In this Review, the authors provide an overview of ditan development, from the initial rationale to the clinical studies that led to the recent FDA approval of the first ditan.

Dimos D. Mitsikostas
Christian Waeber
Michael A. Moskowitz
Reviews12 Jul 2023
Nature Reviews Neurology

Volume: 19, P: 489-505
Subsequent female breast cancer risk associated with anthracycline chemotherapy for childhood cancer

In a pooled analysis of six international studies involving about 17,900 female survivors of childhood cancer, the use of doxorubicin was associated with a dose-dependent risk of subsequent breast cancer, irrespective of prior chest radiotherapy exposure.

Yuehan Wang
Cécile M. Ronckers
Jeanette F. Winther
ResearchOpen Access11 Sept 2023
Nature Medicine

Volume: 29, P: 2268-2277
Addendum: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev
Zhihong Huang
Junying Yuan
Amendments and Corrections15 Feb 2013
Nature Chemical Biology

Volume: 9, P: 192
Hypertension in mice lacking the gene for endothelial nitric oxide synthase

Paul L. Huang
Zhihong Huang
Mark C. Fishman
Research21 Sept 1995
Nature

Volume: 377, P: 239-242
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model

Hayrunnisa Bolay
Uwe Reuter
Michael A. Moskowitz
Research01 Feb 2002
Nature Medicine

Volume: 8, P: 136-142
Author Correction: Duvelisib plus romidepsin in relapsed/refractory T cell lymphomas: a phase 1b/2a trial

Steven M. Horwitz
Ajit J. Nirmal
Santosha A. Vardhana
Amendments and Corrections15 Nov 2024
Nature Medicine

Volume: 30, P: 3778
Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations

Cortical spreading depressions and spreading depolarizations are associated with migraines and stroke, respectively. In this Review, Pietrobon and Moskowitz discuss recent data that provide insight into the mechanisms underlying the initiation and propagation of cortical spreading depressions and spreading depolarizations, and highlight the therapeutic potential of pharmacological targeting of these mechanisms.

Daniela Pietrobon
Michael A. Moskowitz
Reviews20 May 2014
Nature Reviews Neuroscience

Volume: 15, P: 379-393
IS ALTERED OXYGEN TRANSPORT THE MACHANISM FOR INCREASED LEFT VETRICULAR THICKNESS IN PASSIVE SMOKING CHILDREN?

William B Moskowitz
Joann N Bodurtha
Richard M Schieken
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 259
Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network

Sweat, Cao et al. used different genetic and epigenetic approaches to show that Tbx5 is essential for the maintenance of atrial identity in postnatal cardiomyocytes by binding atrial-specific enhancers and maintaining the atrial-specific chromatin architecture, in a dose-dependent manner.

Mason E. Sweat
Yangpo Cao
William T. Pu
Research12 Oct 2023
Nature Cardiovascular Research

Volume: 2, P: 881-898
Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction

Zhang et al. show that bone marrow fatty acid metabolism fuels expanded leukocyte production after myocardial infarction and, based on mouse, pig and human data, suggest that lipolysis in marrow adipocytes provides fatty acids to hematopoietic stem cells.

Shuang Zhang
Alexandre Paccalet
Matthias Nahrendorf
Research05 Dec 2023
Nature Cardiovascular Research

Volume: 2, P: 1277-1290
Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation

Here the authors combine an experimental and analytical approach that integrates single cell epigenomics with GWAS to prioritize risk variants and genes to provide a comprehensive map of Atrial Fibrillation risk variants and genes.

Alan Selewa
Kaixuan Luo
Sebastian Pott
ResearchOpen Access17 Aug 2023
Nature Communications

Volume: 14, P: 1-18
MID-ARM CIRCUMFERENCE/HEAD CIRCUMFERENCE RATIO (MAC/HC) AS AN F PROTEIN-CALORIE DEPRIVATION IN PRETERM INFANTS

Michael K Georgieff
Sharon R Moskowitz
John B Watkins
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 196
Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A₂

Joseph V. Bonventre
Zhihong Huang
Adam Sapirstein
Research01 Dec 1997
Nature

Volume: 390, P: 622-625
Inter-valley coherent order and isospin fluctuation mediated superconductivity in rhombohedral trilayer graphene

Trilayer graphene was recently shown to exhibit superconductivity without a Moire pattern that had proved important in tuning superconductivity in bilayer graphene. Here, the authors explore correlated metallic phases and the pairing mechanism of superconductivity in trilayer graphene, and show that intervalley coherent fluctuations can act as a pairing glue, giving rise to chiral unconventional superconductivity.

Shubhayu Chatterjee
Taige Wang
Michael P. Zaletel
ResearchOpen Access12 Oct 2022
Nature Communications

Volume: 13, P: 1-10
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev
Zhihong Huang
Junying Yuan
Research29 May 2005
Nature Chemical Biology

Volume: 1, P: 112-119
Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia

Jörg B Schulz
Michael Weller
Thomas Klockgether
Research22 Oct 1998
Cell Death & Differentiation

Volume: 5, P: 847-857
Author Correction: Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome

Cristina E. Trevino
Aaron M. Holleman
Michael E. Zwick
Amendments and CorrectionsOpen Access20 Jul 2021
Scientific Reports

Volume: 11, P: 1-2
Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration

The authors describe microscopic channels that directly connect the skull marrow cavities with the meninges. Neutrophils originating from the skull marrow have a higher propensity to travel to the ischemic mouse brain than cells in the tibia.

Fanny Herisson
Vanessa Frodermann
Matthias Nahrendorf
Research27 Aug 2018
Nature Neuroscience

Volume: 21, P: 1209-1217
Selective inactivation or reconstitution of adenosine A_2A receptors in bone marrow cells reveals their significant contribution to the development of ischemic brain injury

Liqun Yu
Zhihong Huang
Jiang-Fan Chen
Research26 Sept 2004
Nature Medicine

Volume: 10, P: 1081-1087
Cerebrospinal Fluid Biogenic Amine Metabolites in Children during Treatment for Acute Lymphocytic Leukemia

Faye S Silverstein
Raymond J Hutchinson
Michael V Johnston
Research01 Apr 1986
Pediatric Research

Volume: 20, P: 285-291
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2

Garry Cutting and colleagues report a genome-wide association and linkage study for loci that affect lung disease severity in cystic fibrosis. They identify two loci that influence lung function in individuals with cystic fibrosis.

Fred A Wright
Lisa J Strug
Garry R Cutting
Research22 May 2011
Nature Genetics

Volume: 43, P: 539-546
863 DIFFERENTIAL EFFECTS OF FOLINIC ACID (FA) AND GLYCINE, ADENOSINE, THYMIDINE (GAT) ON METHOTREXATE (MTX) TOXICITY IN CULTURED HUMAN CELLS

David S Rosenblatt
V Michael Whitehead
Denise Beaulieu
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 586
DECREASED CONTRACTILITY OF THE DUCTUS ARTERIOSUS IN EXPERIMENTAL PULMONIC STENOSIS

Lynn Mahony
Ronald Clyman
Michael Heymann
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 127
Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription

Functional characterization of chromatin enriched lncRNAs (cheRNAs) reveals their role as cis-acting transcriptional activators that couple enhancers at sites of cheRNA synthesis to promoters of proximal target genes.

Michael S Werner
Matthew A Sullivan
Alexander J Ruthenburg
Research19 Jun 2017
Nature Structural & Molecular Biology

Volume: 24, P: 596-603
Cryo-scanning transmission electron tomography of vitrified cells

Cryo-scanning transmission electron tomography (CSTET) of unstained, fully hydrated vitrified biological specimens is shown to have advantages over cryo-electron tomography (CET), notably at high sample tilts providing greater depth resolution for thick samples.

Sharon Grayer Wolf
Lothar Houben
Michael Elbaum
Research16 Feb 2014
Nature Methods

Volume: 11, P: 423-428
Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome

Cristina E. Trevino
Aaron M. Holleman
Michael E. Zwick
ResearchOpen Access22 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
Gut microbiota modulates weight gain in mice after discontinued smoke exposure

A study of mice exposed to cigarette smoke suggests that smoking-cessation-induced weight gain is associated with a dysbiotic state that is driven by smoking-related metabolites.

Leviel Fluhr
Uria Mor
Eran Elinav
Research08 Dec 2021
Nature

Volume: 600, P: 713-719
Experimental Neuronal Injury in the Newborn Lamb: A Comparison of N-Methyl-D-Aspartic Acid Receptor Blockade and Nitric Oxide Synthesis Inhibition on Lesion Size and Cerebral Hyperemia

George A Taylor
William H Trescher
Richard J Traystman
Research01 Nov 1995
Pediatric Research

Volume: 38, P: 644-651
Effects of Nitroprusside on Cardiac Function, Blood Flow Distribution, and Oxygen Consumption in the Conscious Young Lamb

Jaap R G Kuipers
Daniel Sidi
Abraham M Rudolph
Research01 Jul 1984
Pediatric Research

Volume: 18, P: 618-626
Making headway — a role for CGRP in post-traumatic headache

Although common, post-traumatic headache remains poorly understood and poorly treated. New data have implicated calcitonin gene-related peptide and the trigeminovascular system in this disorder, opening up new avenues for research into its pathophysiology and treatment.

Dimos D. Mitsikostas
Michael A. Moskowitz
News & Views16 Nov 2020
Nature Reviews Neurology

Volume: 17, P: 133-134
Mechanisms, challenges and opportunities in stroke

Eng H. Lo
Turgay Dalkara
Michael A. Moskowitz
Reviews01 May 2003
Nature Reviews Neuroscience

Volume: 4, P: 399-414
Aminoglycoside antibiotics induce bacterial biofilm formation

Lucas R. Hoffman
David A. D'Argenio
Samuel I. Miller
Research25 Aug 2005
Nature

Volume: 436, P: 1171-1175
Vitamin therapy in sepsis

Eric L. Wald
Colleen M. Badke
L. Nelson Sanchez-Pinto
Reviews31 Jul 2021
Pediatric Research

Volume: 91, P: 328-336
The clinical impact of bacterial biofilms

Niels Høiby
Oana Ciofu
Thomas Bjarnsholt
Reviews01 Apr 2011
International Journal of Oral Science

Volume: 3, P: 55-65
Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex

Dita M Rasper
John P Vaillancourt
Donald W Nicholson
Research07 Apr 1998
Cell Death & Differentiation

Volume: 5, P: 271-288
Skull bone marrow channels as immune gateways to the central nervous system

Recent discoveries highlight the skull bone marrow, linked to the CNS via osseous channels, as a key neuroimmune compartment. Here, the authors discuss the anatomy, functions and implications of this immune reservoir on CNS health and disease.

Jose A. Mazzitelli
Fadi E. Pulous
Matthias Nahrendorf
Reviews23 Nov 2023
Nature Neuroscience

Volume: 26, P: 2052-2062

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