Nature Search

tRNA-dependent asparagine formation

Alan W. Curnow
Michael Ibba
Dieter Söll
Research15 Aug 1996
Nature

Volume: 382, P: 589-590
Battle of the DNA sequencers

There are now three automated DNA sequencers on the market — from Du Pont, Applied Biosystems, and EG & G Biomolecular. Below each company tells why theirs is best.

Edward Chait
Guy Page
Michael Hunkapiller
Comments & Opinion02 Jun 1988
Nature

Volume: 333, P: 477-478
Comprehensive analysis of diverse ribonucleoprotein complexes

Marlene Oeffinger
Karen E Wei
Michael P Rout
Research07 Oct 2007
Nature Methods

Volume: 4, P: 951-956
Conformation of GroEL-bound α-lactalbumin probed by mass spectrometry

Carol V. Robinson
Michael Groß
Sheena E. Radford
Research15 Dec 1994
Nature

Volume: 372, P: 646-651
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

Gabriel Waksman
Dorothea Kominos
John Kuriyan
Research20 Aug 1992
Nature

Volume: 358, P: 646-653
SNAP receptors implicated in vesicle targeting and fusion

Thomas Söllner
Sidney W. Whiteheart
James E. Rothman
Research25 Mar 1993
Nature

Volume: 362, P: 318-324
Determining the architectures of macromolecular assemblies

Frank Alber
Svetlana Dokudovskaya
Andrej Sali
Research29 Nov 2007
Nature

Volume: 450, P: 683-694
The molecular architecture of the nuclear pore complex

Frank Alber
Svetlana Dokudovskaya
Michael P. Rout
Research29 Nov 2007
Nature

Volume: 450, P: 695-701
Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

Nuclear pore complexes (NPCs) serve as gateways between the nucleus and cytoplasm and allow only the transport of selected macromolecules across the nuclear envelope. NPCs are comprised of a scaffold that anchors proteins called FG-nucleoporins, which contain disordered regions that line the inner surface of the pore and extend into the lumen. This study reports the design of an artificial membrane that functions as a selective filter in allowing efficient passage of transport factors and transport factor carrying cargo that specifically bind to FG-nucleoporins.

Tijana Jovanovic-Talisman
Jaclyn Tetenbaum-Novatt
Brian T. Chait
Research21 Dec 2008
Nature

Volume: 457, P: 1023-1027
A robust pipeline for rapid production of versatile nanobody repertoires

This paper presents an efficient method for generating nanobodies with high affinity and high specificity. In addition, a collection of nanobodies specific for GFP or mCherry that resulted from this work is described.

Peter C Fridy
Yinyin Li
Michael P Rout
Research02 Nov 2014
Nature Methods

Volume: 11, P: 1253-1260
In utero induction and development of brain β-hydroxybutyrate dehydrogenase (BDH)

M Michael Thaler
Max M Chait
Research01 Aug 1971
Pediatric Research

Volume: 5, P: 373
Integrative structure and functional anatomy of a nuclear pore complex

The structure of the yeast nuclear pore complex, determined at sub-nanometre precision using an integrative approach that combines a wide range of data, reveals details of its architecture, transport mechanism and evolutionary origins.

Seung Joong Kim
Javier Fernandez-Martinez
Michael P. Rout
Research14 Mar 2018
Nature

Volume: 555, P: 475-482
Rapid, optimized interactomic screening

Extraction conditions can have a substantial effect on protein complexes isolated from within cells. A platform for rapid, systematic screening of these conditions is described, which should enable the identification of biologically relevant complexes.

Zhanna Hakhverdyan
Michal Domanski
John LaCava
Research04 May 2015
Nature Methods

Volume: 12, P: 553-560
Individualized anemia management enhanced by ferric pyrophosphate citrate protocol

Yossi Chait
Brian H. Nathanson
Michael J. Germain
ResearchOpen Access22 Nov 2022
Scientific Reports

Volume: 12, P: 1-7
C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site

The crystal structure of human replication and transcription cofactor PC4_CTD reveals a dimer with two single-stranded (ss)DNA binding channels running in opposite directions to each other. This arrangement suggests a role in establishment or maintenance of melted DMA at promoters or origins of replication.

Jeroen Brandsen
Sebastiaan Werten
Piet Gros
Correspondence01 Nov 1997
Nature Structural Biology

Volume: 4, P: 900-903
HIV–host interactome revealed directly from infected cells

Fully replication competent HIV-1 viruses engineered to harbour a foreign epitope tag enabled the unbiased characterization of the cellular interactomes of viral Env and Vif proteins during the natural infection of human lymphocytes.

Yang Luo
Erica Y. Jacobs
Mark A. Muesing
Research23 May 2016
Nature Microbiology

Volume: 1, P: 1-15
UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

Eukaryotic ribosome biogenesis involves a large number of maturations factors which are responsible for the stepwise assembly of the ribosomal subunits. Here the authors use an array of biochemical and structural biology methods to investigate the function of the UtpA and UtpB complexes as part of the small subunit processome.

Mirjam Hunziker
Jonas Barandun
Sebastian Klinge
ResearchOpen Access29 Jun 2016
Nature Communications

Volume: 7, P: 1-10
The architecture of a eukaryotic replisome

Single-particle electron microscopy reconstruction of the budding yeast replisome locates leading-strand Pol ε and lagging-strand Pol α on opposite sides of the CMG helicase and suggests a new DNA path through the complex during replication.

Jingchuan Sun
Yi Shi
Michael E O'Donnell
Research02 Nov 2015
Nature Structural & Molecular Biology

Volume: 22, P: 976-982
Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum

Farber and colleagues report distinct antibody responses to SARS-CoV-2 in pediatric cohorts, including those who developed multisystem inflammatory syndrome (MIS-C), and adult COVID-19 cohorts.

Stuart P. Weisberg
Thomas J. Connors
Donna L. Farber
Research05 Nov 2020
Nature Immunology

Volume: 22, P: 25-31
A strategy for dissecting the architectures of native macromolecular assemblies

The molecular architecture of protein complexes can be determined using an optimal approach for isolating GFP-tagged complexes at native levels, combined with cross-linking, mass spectrometry analysis, and structure modeling from mass spectrometry-derived distance restraints.

Yi Shi
Riccardo Pellarin
Brian T Chait
Research05 Oct 2015
Nature Methods

Volume: 12, P: 1135-1138
Efficient cotransduction of tumors by multiple herpes simplex vectors: Implications for tumor vaccine production

Howard M Karpoff
David Kooby
Yuman Fong
Research15 Jun 2000
Cancer Gene Therapy

Volume: 7, P: 581-588
Light-assisted small-molecule screening against protein kinases

The combination of a light-activated receptor tyrosine kinase and a fluorescent MAPK/ERK reporter results in the development of an optogenetics-based cell screening method to identify small-molecule inhibitors of RTK signaling.

Álvaro Inglés-Prieto
Eva Reichhart
Harald Janovjak
Research12 Oct 2015
Nature Chemical Biology

Volume: 11, P: 952-954
Compounds that select against the tetracycline-resistance efflux pump

A high-throughput screen against the E. coli tetracycline-resistance efflux pump TetA identifies two ‘selection-inverting’ compounds that swap tetracycline resistance for resistance to another antibiotic, paving the way for two-phase antibiotic treatment protocols.

Laura K Stone
Michael Baym
Roy Kishony
Research19 Sept 2016
Nature Chemical Biology

Volume: 12, P: 902-904
Phosphoric Acid Entrapment Leads to Apparent Protein Heterogeneity

Michael Fountoulakis
Francis Vilbois
Walter Vetter
Research01 Apr 1995
Bio/Technology

Volume: 13, P: 383-388
Effects of Smoking Marijuana on Brain Perfusion and Cognition

Daniel S O'Leary
Robert I Block
Richard D Hichwa
Research30 Nov 2001
Neuropsychopharmacology

Volume: 26, P: 802-816
Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies

Nikola Kellner
Johannes Schwarz
Ed Hurt
ResearchOpen Access11 Feb 2016
Scientific Reports

Volume: 6, P: 1-10

Search

tRNA-dependent asparagine formation

Battle of the DNA sequencers

Comprehensive analysis of diverse ribonucleoprotein complexes

Conformation of GroEL-bound α-lactalbumin probed by mass spectrometry

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

SNAP receptors implicated in vesicle targeting and fusion

Determining the architectures of macromolecular assemblies

The molecular architecture of the nuclear pore complex

Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

A robust pipeline for rapid production of versatile nanobody repertoires

In utero induction and development of brain β-hydroxybutyrate dehydrogenase (BDH)

Integrative structure and functional anatomy of a nuclear pore complex

Rapid, optimized interactomic screening

Individualized anemia management enhanced by ferric pyrophosphate citrate protocol

C-terminal domain of transcription cofactor PC4 reveals dimeric ssDNA binding site

HIV–host interactome revealed directly from infected cells

UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly

The architecture of a eukaryotic replisome

Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum

A strategy for dissecting the architectures of native macromolecular assemblies

Efficient cotransduction of tumors by multiple herpes simplex vectors: Implications for tumor vaccine production

Light-assisted small-molecule screening against protein kinases

Compounds that select against the tetracycline-resistance efflux pump

Phosphoric Acid Entrapment Leads to Apparent Protein Heterogeneity

Effects of Smoking Marijuana on Brain Perfusion and Cognition

Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies

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