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Showing 101–150 of 180 results

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Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia

Michael A. Kiebish
Poornima Tekumalla
Niven R. Narain
ResearchOpen Access23 Jul 2021
Scientific Reports

Volume: 11, P: 1-9
Increased frequency of germline BRCA2 mutations associates with prostate cancer metastasis in a racially diverse patient population

Gyorgy Petrovics
Douglas K. Price
Michael Dean
ResearchOpen Access12 Dec 2018
Prostate Cancer and Prostatic Diseases

Volume: 22, P: 406-410
The retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity

PNMA-family genes are gag-like elements of ancient retrotransposon origin whose roles in mammalian genomes is incompletely understood. Wood et al. found that two retrotransposon-derived proteins, PNMA1 and PNMA4, support mammalian fertility in both sexes and become increasingly important during aging. These proteins assemble into capsid-like structures that contain RNA and exit human cells.

Thomas W. P. Wood
William S. Henriques
Luke E. Berchowitz
Research22 Apr 2025
Nature Aging

Volume: 5, P: 765-779
A mesoscale phytoplankton bloom in the polar Southern Ocean stimulated by iron fertilization

Philip W. Boyd
Andrew J. Watson
John Zeldis
Research12 Oct 2000
Nature

Volume: 407, P: 695-702
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

Ross A Dickins
Michael T Hemann
Scott W Lowe
Research02 Oct 2005
Nature Genetics

Volume: 37, P: 1289-1295
Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)

Diego Martinez
Randy M Berka
Thomas S Brettin
ResearchOpen Access04 May 2008
Nature Biotechnology

Volume: 26, P: 553-560
Addressing the isomer cataloguing problem for nanopores in two-dimensional materials

Nanopores in 2D materials have various possible lattice isomers, making relevant quantitative analysis difficult. An isomer-cataloguing framework is developed to address this problem, demonstrating remarkable agreement between simulated and experimental data.

Ananth Govind Rajan
Kevin S. Silmore
Michael S. Strano
Research14 Jan 2019
Nature Materials

Volume: 18, P: 129-135
Functional annotation of rare gene aberration drivers of pancreatic cancer

Next generation sequencing allows the identification of oncogenic driver genes in pancreatic cancer. Here, in an effort to identify additional causal genes, the authors develop a high throughput in vivoscreen and identify genes that whilst infrequently mutated in pancreatic cancer contribute to tumour formation.

Yiu Huen Tsang
Turgut Dogruluk
Kenneth L. Scott
ResearchOpen Access25 Jan 2016
Nature Communications

Volume: 7, P: 1-11
mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo

In Alzheimer's disease, the soluble amyloid beta peptide is known to modulate synaptic function by forming a complex with prion proteins and metabotropic glutamate receptors. Here, Hu et al.show that amyloid beta signalling via this complex facilitates the induction of long-term depression at synapses.

Neng-Wei Hu
Andrew J. Nicoll
Michael J. Rowan
ResearchOpen Access04 Mar 2014
Nature Communications

Volume: 5, P: 1-13
The state of food systems worldwide in the countdown to 2030

Holistic indicator frameworks are needed to track food systems transformation. This Analysis shows the application of a framework recently developed by the Food Systems Countdown Initiative to all UN member states, revealing current status, data gaps and priority actions.

Kate R. Schneider
Jessica Fanzo
Keith Wiebe
ResearchOpen Access19 Dec 2023
Nature Food

Volume: 4, P: 1090-1110
Author Correction: BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

Linus Manubens-Gil
Zhi Zhou
Hanchuan Peng
Amendments and Corrections02 Aug 2024
Nature Methods

Volume: 21, P: 1959
Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus

Lin Xu
Roger Anwyl
Michael J. Rowan
Research27 Aug 1998
Nature

Volume: 394, P: 891-894
Expression of the Escherichia coli Enterotoxin Subunit B Gene in Aspergillus nidulans Directed by the AMDS Promoter

Ian F. Turnbull
Keith Rand
Michael J. Hynes
Research01 Feb 1989
Bio/Technology

Volume: 7, P: 169-174
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus

Peter Donnelly and colleagues report a genome-wide association study for Barrett's esophagus, a common premalignant condition associated with stomach acid reflux and predisposing to esophageal adenocarcinoma. They identify two loci associated with susceptibility to Barrett's esophagus.

Zhan Su
Laura J Gay
Janusz A Z Jankowski
Research09 Sept 2012
Nature Genetics

Volume: 44, P: 1131-1136
Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

David V. Conti
Burcu F. Darst
Christopher A. Haiman
Amendments and Corrections20 Jan 2021
Nature Genetics

Volume: 53, P: 413
No impacts of glyphosate or Crithidia bombi, or their combination, on the bumblebee microbiome

Edward A. Straw
Robin Mesnage
Michael N. Antoniou
ResearchOpen Access02 Jun 2023
Scientific Reports

Volume: 13, P: 1-8
Bcl-2 inhibits c-fos induction by calcium

Xiao-Mei Qi
Michael Simonson
Clark W Distelhorst
Research04 Dec 1997
Oncogene

Volume: 15, P: 2849-2853
Echocardiography and lung ultrasonography for the assessment and management of acute heart failure

The successful management of patients with acute heart failure (AHF) involves early diagnosis, rapid identification of underlying causes, and immediate implementation of effective therapies. In this Consensus Statement, the AHF Study Group of the ESC Acute Cardiovascular Care Association reviews the roles of echocardiography and lung ultrasonography in the assessment and management of patients with AHF.

Susanna Price
Elke Platz
Christian Mueller
ReviewsOpen Access27 Apr 2017
Nature Reviews Cardiology

Volume: 14, P: 427-440
Reply to "Origin of logarithmic resistance correction in graphene"

Jian-Hao Chen
Liang Li
Michael S. Fuhrer
Correspondence02 May 2012
Nature Physics

Volume: 8, P: 353
PSYSCAN multi-centre study: baseline characteristics and clinical outcomes of the clinical high risk for psychosis sample

Stefania Tognin
Sandra Vieira
Philip McGuire
ResearchOpen Access17 Apr 2025
Schizophrenia

Volume: 11, P: 1-9
Vestibular patients generate more regular head movements than healthy individuals during gaze-stabilization exercises

Cecelia Shuai
Omid A. Zobeiri
Kathleen E. Cullen
ResearchOpen Access07 Jan 2025
Scientific Reports

Volume: 15, P: 1-17
BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

This resource describes a collection of neurons from a variety of light microscopy-based datasets, which can serve as a gold standard for testing automated tracing algorithms, as shown by comparison of the performance of 35 algorithms.

Linus Manubens-Gil
Zhi Zhou
Hanchuan Peng
Research17 Apr 2023
Nature Methods

Volume: 20, P: 824-835
Bio-inspired electronics: Soft, biohybrid, and “living” neural interfaces

Neural technologies are adopting bio-inspired designs to enhance biointegration and functionality. This review maps the growing field of bio-inspired electronics and discusses recent developments in tissue-like bioelectronics, from soft interfaces to ‘biohybrid’ and ‘all-living’ platforms.

Dimitris Boufidis
Raghav Garg
Flavia Vitale
ReviewsOpen Access21 Feb 2025
Nature Communications

Volume: 16, P: 1-17
Improved Production of Chymosin in Aspergillus by Expression as a Glucoamylase-Chymosin Fusion

Michael Ward
Lori J. Wilson
Randy M. Berka
Research01 May 1990
Bio/Technology

Volume: 8, P: 435-440
Commercial Levels of Chymosin Production by Aspergillus

Nigel S. Dunn-Coleman
Peggy Bloebaum
Henry Heinsohn
Research01 Oct 1991
Bio/Technology

Volume: 9, P: 976-981
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma

Maria Teresa Landi and colleagues identify a rare missense variant in POT1 shared by five melanoma-prone families from Italy and associated with increased telomere length and telomere fragility. They also identify additional familial melanoma cases with rare missense variants in POT1 and find a significant excess of rare exonic POT1 variants in melanoma cases compared to controls, implicating POT1 variants in melanoma susceptibility.

Jianxin Shi
Xiaohong R Yang
Maria Teresa Landi
Research30 Mar 2014
Nature Genetics

Volume: 46, P: 482-486
Nuclear transport erupts on the slopes of Mount Etna

Maureen A. Powers
Mary Dasso
News & Views01 Feb 2004
Nature Cell Biology

Volume: 6, P: 82-86
Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11

Thomas A. Ravenscroft
Jennifer B. Phillips
Hugo J. Bellen
Research10 Jun 2021
Genetics in Medicine

Volume: 23, P: 1889-1900
THE EFFECT OF EARLY ADEQUATE CALORIE INTAKE IN LOW BIRTH WEIGHT INFANTS

Kunnikar Tanprasert
Yeai Roan
Samuel S Spector
Research01 Apr 1974
Pediatric Research

Volume: 8, P: 386
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Innervation: the missing link for biofabricated tissues and organs

Suradip Das
Wisberty J. Gordián-Vélez
D. Kacy Cullen
ReviewsOpen Access05 Jun 2020
npj Regenerative Medicine

Volume: 5, P: 1-19
Effect of vestibular loss on head-on-trunk stability in individuals with vestibular schwannoma

Raabeae Aryan
Omid A. Zobeiri
Kathleen E. Cullen
ResearchOpen Access12 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
Head movement kinematics are differentially altered for extended versus short duration gait exercises in individuals with vestibular loss

Jennifer L. Millar
Omid A. Zobeiri
Kathleen E. Cullen
ResearchOpen Access27 Sept 2023
Scientific Reports

Volume: 13, P: 1-13
Severe aortic and arterial aneurysms associated with a TGFBR2 mutation

Scott A LeMaire
Hariyadarshi Pannu
Dianna M Milewicz
Reviews01 Mar 2007
Nature Clinical Practice Cardiovascular Medicine

Volume: 4, P: 167-171
Kluyveromyces as a Host for Heterologous Gene Expression: Expression and Secretion of Prochymosin

Johan A. van den Berg
Kees J. van der Laken
Jeffrey R. Shuster
Research01 Feb 1990
Bio/Technology

Volume: 8, P: 135-139
Low birth weight is associated with impaired murine kidney development and function

Christina Barnett
Oluwadara Nnoli
Brian B Ratliff
Research31 May 2017
Pediatric Research

Volume: 82, P: 340-348
A High Capacity Assay for Inhibitors of Human Papillomavirus DNA Replication

Mary Plumpton
Nigel A. Sharp
Michael A. Romanos
Research01 Nov 1995
Bio/Technology

Volume: 13, P: 1210-1214
Structure of acid β-glucosidase with pharmacological chaperone provides insight into Gaucher disease

Raquel L Lieberman
Brandon A Wustman
Gregory A Petsko
Research24 Dec 2006
Nature Chemical Biology

Volume: 3, P: 101-107
Head movement kinematics are altered during gaze stability exercises in vestibular schwannoma patients

Lin Wang
Omid A. Zobeiri
Kathleen E. Cullen
ResearchOpen Access30 Mar 2021
Scientific Reports

Volume: 11, P: 1-15
Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion

In vivo extracellular recordings in pigs reveal that concussion preferentially disrupts the activity of hippocampal interneurons leading to network hyperexcitability, with in silico models implicating altered voltage-gated sodium channel kinetics.

Alexandra V. Ulyanova
Christopher D. Adam
John A. Wolf
ResearchOpen Access09 Nov 2023
Communications Biology

Volume: 6, P: 1-13
An implantable human stem cell-derived tissue-engineered rostral migratory stream for directed neuronal replacement

O’Donnell et al. describe their Tissue-Engineered Rostral Migratory Stream (TE-RMS) comprised of human astrocyte-like cells that can be derived from adult gingival stem cells within one week, which reorganizes into bundles of bidirectional, longitudinally-aligned astrocytes to emulate the endogenous RMS. Establishing immature neuronal migration in vitro and in vivo, their study demonstrates surgical feasibility and proof-of-concept evidence for this nascent technology.

John C. O’Donnell
Erin M. Purvis
D. Kacy Cullen
ResearchOpen Access15 Jul 2021
Communications Biology

Volume: 4, P: 1-16
Pharmacological ascorbate inhibits pancreatic cancer metastases via a peroxide-mediated mechanism

Brianne R. O’Leary
Matthew S. Alexander
Joseph J. Cullen
ResearchOpen Access19 Oct 2020
Scientific Reports

Volume: 10, P: 1-13
Toward personalized synchrotron microbeam radiation therapy

Elette Engels
Nan Li
Moeava Tehei
ResearchOpen Access01 Jun 2020
Scientific Reports

Volume: 10, P: 1-13
Founder effects and geographic variation in the land snail Theba pisana

Michael S Johnson
Research01 Aug 1988
Heredity

Volume: 61, P: 133-142
Heterologous Gene Expression in Hansenula Polymorpha: Efficient Secretion of Glucoamylase

Gerd Gellissen
Zbigniew A. Janowicz
Alexander W.M. Strasser
Research01 Mar 1991
Bio/Technology

Volume: 9, P: 291-295
N-Glycosylation of Recombinant Human Interferon-γ Produced in Different Animal Expression Systems

David C. James
Robert B. Freedman
Nigel Jenkins
Research01 Jun 1995
Bio/Technology

Volume: 13, P: 592-596
Emerging regenerative medicine and tissue engineering strategies for Parkinson’s disease

James P. Harris
Justin C. Burrell
D. Kacy Cullen
ReviewsOpen Access08 Jan 2020
npj Parkinson's Disease

Volume: 6, P: 1-14
Polyamines in cancer: integrating organismal metabolism and antitumour immunity

This Perspective discusses how polyamines, polyamine metabolism, the microbiota and the diet interconnect to establish a tumour microenvironment that facilitates the initiation and progression of cancer. It also details ways in which polyamine metabolism and function can be targeted for therapeutic benefit, including specifically enhancing the antitumour immune response.

Cassandra E. Holbert
Michael T. Cullen
Tracy Murray Stewart
Reviews27 Apr 2022
Nature Reviews Cancer

Volume: 22, P: 467-480
Bamboo orbital foreign body mimicking air on computed tomography

Michael J Greaney
Correspondence01 Nov 1994
Eye

Volume: 8, P: 713-714
Biomimetic cellular vectors for enhancing drug delivery to the lungs

Michael Evangelopoulos
Iman K. Yazdi
Ennio Tasciotti
ResearchOpen Access13 Jan 2020
Scientific Reports

Volume: 10, P: 1-10

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