The prevalence of increased blood pressure during sleep and a blunted sleep-time-relative blood pressure decline is high in patients with chronic kidney disease (CKD) and increases with disease severity. Here, the authors describe 24 h blood pressure variation and discuss data suggesting that bedtime dosing of hypertension medications might improve blood pressure control and reduce cardiovascular risk in hypertensive patients, including those with CKD.
- Ramón C. Hermida
- Diana E. Ayala
- Francesco Portaluppi
