Elucidating protein profiles that can provide diagnostic and prognostic information is the aim of an increasing number of proteomics projects. This daunting task is being advanced by the continual improvement of high-throughput technologies. Here, Michael Goligorsky and colleagues introduce us to these techniques, and describe how they might be applied to renal tissues and urine. Data from early studies of diseases of native and grafted kidneys are presented.
- Edmond O'Riordan
- Steven S Gross
- Michael S Goligorsky
