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Showing 1–4 of 4 results
Advanced filters: Author: Michael W. Grome Clear advanced filters

  • Ochre, a strain of Escherichia coli engineered to have a single stop codon, enables reassignment of four codons for non-degenerate functions, such as incorporation of non-standard amino acids into proteins.

    • Michael W. Grome
    • Michael T. A. Nguyen
    • Farren J. Isaacs
    ResearchOpen Access
    Nature
    Volume: 639, P: 512-521

  • Randomised controlled experiments are the gold standard for scientific inference, but environmental and social scientists often rely on different study designs. Here the authors analyse the use of six common study designs in the fields of biodiversity conservation and social intervention, and quantify the biases in their estimates.

    • Alec P. Christie
    • David Abecasis
    • William J. Sutherland
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • Construction of a series of genomically recoded organisms whose growth is restricted by the expression of essential genes dependent on exogenously supplied synthetic amino acids introduces novel orthogonal barriers between these engineered organisms and the environment, thereby creating safer genetically modified organisms.

    • Alexis J. Rovner
    • Adrian D. Haimovich
    • Farren J. Isaacs
    Research
    Nature
    Volume: 518, P: 89-93