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Showing 1–3 of 3 results
Advanced filters: Author: Michelle Y. Jaeckstein Clear advanced filters

  • Reverte-Salisa et al. show that, in preadipocytes, EPAC1 enhances brown adipose tissue growth and increases the function of thermogenic fat in obesogenic conditions. Activation of EPAC1 induces human brown adipocyte proliferation and differentiation.

    • Laia Reverte-Salisa
    • Sana Siddig
    • Alexander Pfeifer
    ResearchOpen Access
    Nature Cell Biology
    Volume: 26, P: 113-123

  • Mitochondria have a pivotal role in the transport of dietary lipids in enterocytes, a finding that might have relevance to understanding the aberrant gastrointestinal function in patients with mitochondrial disorders.

    • Chrysanthi Moschandrea
    • Vangelis Kondylis
    • Manolis Pasparakis
    ResearchOpen Access
    Nature
    Volume: 625, P: 385-392

  • Untargeted metabolomics demonstrate that apoptotic brown adipocytes release a specific pattern of metabolites with purine metabolites being highly enriched, and inosine is identified as a metabolite released during apoptosis regulating thermogenic fat and counteracting obesity.

    • Birte Niemann
    • Saskia Haufs-Brusberg
    • Alexander Pfeifer
    ResearchOpen Access
    Nature
    Volume: 609, P: 361-368