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Showing 1–4 of 4 results
Advanced filters: Author: Mieko Higuchi-Takeuchi Clear advanced filters
  • Academia and industry are interested in using autotrophic microorganisms as a sustainable/green production platform to produce biochemical products and commercially relevant commodities, including biopolymers. Unlike heterotrophs that require carbohydrates and amino acids for growth, autotrophs have evolved to fix carbon dioxide and drive metabolic processes utilizing either light (photoautotrophs) or chemical compounds (chemolithotrophs) as energy sources. Here, we review the current state-of-the-art in the construction of autotrophic microbial cell factories for efficient biopolymer production and recent breakthroughs in natural autotrophs focusing on biopolymer production.

    • Pisanee Srisawat
    • Mieko Higuchi-Takeuchi
    • Keiji Numata
    ReviewsOpen Access
    Polymer Journal
    Volume: 54, P: 1139-1151
  • Foong et al. demonstrate production of spider dragline silk proteins in Rhodovulum sulfidophilum, a marine photosynthetic purple bacterium. This platform generates promise for the sustainable production of valuable biocompounds in photosynthetic organisms.

    • Choon Pin Foong
    • Mieko Higuchi-Takeuchi
    • Keiji Numata
    ResearchOpen Access
    Communications Biology
    Volume: 3, P: 1-8
  • Bacteria possibly capable of polyhydroxyalkanoate synthesis from lignin were investigated by genomics and chemistry of biomaterials. Aquitalea sp and Ralstonia pickettii isolated from a blackwater lake rich humic substances, showed great potential to be developed for this purpose. Canonical lignin degradation pathways, such as protocatechuate 4,5-dioxygenase-dependent pathway, CoA-dependent non-β-oxidation pathway of ferulic acid and β-ketoadipate pathway were mapped in their genomes. In addition, traces of P(3HB) were found when using vanillic and gallic acids as sole carbon source, which indicates that the downstream β-ketoadipate pathway is functional.

    • Lorena M. Castro
    • Choon Pin Foong
    • Adolfo J. Mota
    Research
    Polymer Journal
    Volume: 53, P: 191-202