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Showing 1–4 of 4 results
Advanced filters: Author: Mihai Azoitei Clear advanced filters

  • A pan-betacoronavirus vaccine will likely require the elicitation of antibodies against spike regions conserved across diverse coronaviruses. Here, authors computationally engineer and experimentally validate immunogens to elicit antibodies against two such spike regions.

    • A. Brenda Kapingidza
    • Daniel J. Marston
    • Mihai L. Azoitei
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-18

  • Immunization of macaques with nanoparticle-conjugated receptor-binding domain of SARS-CoV-2 adjuvanted with 3M-052 and alum results in cross-neutralizing antibodies against bat coronaviruses, SARS-CoV and SARS-CoV-2 variants, and may provide a platform for developing pan-coronavirus vaccines.

    • Kevin O. Saunders
    • Esther Lee
    • Barton F. Haynes
    Research
    Nature
    Volume: 594, P: 553-559

  • Biosensors of guanine exchange factors (GEFs) and red-shifted GTPase biosensors are used to visualize GEF and GTPase activities in the same cells and enable correlation analysis to reveal which GEF–GTPase interactions regulate cell movement.

    • Daniel J. Marston
    • Marco Vilela
    • Klaus M. Hahn
    Research
    Nature Chemical Biology
    Volume: 16, P: 826-833