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Showing 1–2 of 2 results
Advanced filters: Author: Mihir Metkar Clear advanced filters

  • mRNA-1273, an mRNA vaccine that encodes a stabilized prefusion-state severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein, elicits robust immune responses and protects mice against replication of SARS-CoV-2 in the upper and lower airways.

    • Kizzmekia S. Corbett
    • Darin K. Edwards
    • Barney S. Graham
    Research
    Nature
    Volume: 586, P: 567-571

  • The recent success of mRNA vaccines has boosted the prospects for the development of a new class of designer medicines based on mRNA. This Review discusses the multiple design parameters that need to be carefully considered to create highly effective mRNA medicines.

    • Mihir Metkar
    • Christopher S. Pepin
    • Melissa J. Moore
    Reviews
    Nature Reviews Drug Discovery
    Volume: 23, P: 67-83