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Showing 1–5 of 5 results

Advanced filters: Author: Miho K Furue Clear advanced filters

The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction

DOCK8-deficiency can cause atopic dermatitis but the mechanism is unclear. Here the authors use mice and human samples to show ARNT-independent DOCK8 inhibition of EPAS1 increases transcription of IL-31 in CD4⁺T cells, thus driving skin inflammation.

Kazuhiko Yamamura
Takehito Uruno
Yoshinori Fukui
ResearchOpen Access09 Jan 2017
Nature Communications

Volume: 8, P: 1-13
Parametric analysis of colony morphology of non-labelled live human pluripotent stem cells for cell quality control

Ryuji Kato
Megumi Matsumoto
Miho K Furue
ResearchOpen Access26 Sept 2016
Scientific Reports

Volume: 6, P: 1-12
STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch

In response to signals from afferent TRPV1⁺ C-fibers, STAT3-dependent upregulation of LCN2 in reactive astrocytes of the spinal dorsal horn amplifies itch signaling in multiple rodent models of atopic and contact dermatitis.

Miho Shiratori-Hayashi
Keisuke Koga
Makoto Tsuda
Research20 Jul 2015
Nature Medicine

Volume: 21, P: 927-931
Enzyme-free Passage of Human Pluripotent Stem Cells by Controlling Divalent Cations

Kiyoshi Ohnuma
Ayaka Fujiki
Makoto Asashima
ResearchOpen Access11 Apr 2014
Scientific Reports

Volume: 4, P: 1-7
Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours

Keisuke Koga
Kensho Kanehisa
Makoto Tsuda
ResearchOpen Access05 Jul 2017
Scientific Reports

Volume: 7, P: 1-10