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Gingipain regulates isoform switches of PD-L1 in macrophages infected with Porphyromonas gingivalis

Yilin Zheng
Ziyi Wang
Hirohiko Okamura
ResearchOpen Access26 Mar 2025
Scientific Reports

Volume: 15, P: 1-15
Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

Osteoblasts mediate bone formation, and their differentiation requires expression of EphrinB2. Here, the authors show that EphrinB2 is also expressed by osteocytes, and that its genetic ablation in mice is associated with altered autophagy, elevated mineralization and brittle bone.

Christina Vrahnas
Martha Blank
Natalie A. Sims
ResearchOpen Access31 Jul 2019
Nature Communications

Volume: 10, P: 1-16
Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

Christina Vrahnas
Martha Blank
Natalie A. Sims
Amendments and CorrectionsOpen Access04 Nov 2019
Nature Communications

Volume: 10, P: 1
Uptake of osteoblast-derived extracellular vesicles promotes the differentiation of osteoclasts in the zebrafish scale

Kobayashi-Sun et al. characterise the healing of fractured bone in the transgenic zebrafish scale by transplantation assays and live imaging, revealing that immature osteoclasts engulf osteoblast-derived extracellular vesicles (EVs) under fracture stress, leading to osteoclast differentiation. This study provides insights into the role of EVs in osteoclastogenesis.

Jingjing Kobayashi-Sun
Shiori Yamamori
Isao Kobayashi
ResearchOpen Access23 Apr 2020
Communications Biology

Volume: 3, P: 1-12

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Gingipain regulates isoform switches of PD-L1 in macrophages infected with Porphyromonas gingivalis

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone

Uptake of osteoblast-derived extracellular vesicles promotes the differentiation of osteoclasts in the zebrafish scale

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