Nature Search

Erythrocyte Insulin Binding in Preterm Newborn Infants

Raija Puukka
Mikael Knip
Matti Puukka
Research01 Mar 1986
Pediatric Research

Volume: 20, P: 256-260
Nocturnal Release of Immunoreactive Growth Hormone-Releasing Hormone and Growth Hormone in Normal Children

Päivi Tapanainen
Heikki Rantala
Mikael Knip
Research01 Nov 1989
Pediatric Research

Volume: 26, P: 404-409
Clinical Characteristics and Circulating Collagen and Laminin Metabolites in Insulin-Dependent Diabetic Children with Joint and Skin Manifestations

Riitta Veijola
Mikael Knip
Jorma Ilonen
Research01 May 1993
Pediatric Research

Volume: 33, P: 501-505
Metabolic and Hematologic Effects and Immune Complex Formation Related to Pertussis Immunization

Chrisanna M Mink
Matti Uhari
James D Cherry
Research01 Apr 1990
Pediatric Research

Volume: 27, P: 353-357
Type 1 diabetes mellitus is a heterogeneous disease

Mikael Knip
Correspondence07 Jul 2017
Nature Reviews Endocrinology

Volume: 13, P: 1
Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Integration of longitudinal gut metagenomic datasets from children in Finland, Estonia and Russian Karelia reveals high strain-level diversity, which consequently impacts the functional capabilities of the early life microbiome.

Tommi Vatanen
Damian R. Plichta
Ramnik J. Xavier
Research17 Dec 2018
Nature Microbiology

Volume: 4, P: 470-479
Loss of β-cell mass — an acute event before T1DM presentation?

Loss of β-cell mass is posited to occur gradually over a long period of time in preclinical type 1 diabetes mellitus, as the first signs of β-cell autoimmunity generally emerge several years before clinical presentation. This concept has recently been challenged by observations of acute loss of β-cell mass in late-phase preclinical disease.

Mikael Knip
News & Views31 Mar 2017
Nature Reviews Endocrinology

Volume: 13, P: 253-254
Soluble Adhesion Molecules in Preclinical Type 1 Diabetes

Anna Toivonen
Petri Kulmala
Mikael Knip
Research01 Jan 2001
Pediatric Research

Volume: 49, P: 24-29
Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies

Previous studies have reported heterogeneity in the progression to clinical type 1 diabetes in children who develop either insulin- or glutamic acid decarboxylase-specific antibodies as their first autoantibodies. Here, the authors show that children who later develop disease have distinct characteristics in early immune responses, which are dependent on the type of autoantibodies that appear first.

Inna Starskaia
Milla Valta
Riitta Lahesmaa
ResearchOpen Access07 May 2024
Nature Communications

Volume: 15, P: 1-13
The role of the intestinal microbiota in type 1 diabetes mellitus

A growing number of studies have shown changes to gut microbiota in children who go on to develop type 1 diabetes mellitus. This Review discusses the strengths and limitations of existing research, covering animal models of the disease and observational human studies. The technology used to characterize intestinal microbiota and recommendations for future studies are also addressed.

Mikael Knip
Heli Siljander
Reviews04 Jan 2016
Nature Reviews Endocrinology

Volume: 12, P: 154-167
Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan

Centenarians have a diverse population of gut bacteriophages, a subset of which encode sulfate metabolism genes and may promote healthy aging.

Joachim Johansen
Koji Atarashi
Damian R. Plichta
Research15 May 2023
Nature Microbiology

Volume: 8, P: 1064-1078
Insulin Autoantibody Isotypes during the Prediabetic Process in Young Children with Increased Genetic Risk of Type 1 Diabetes

Sanna Hoppu
Matti S Ronkainen
Mikael Knip
Research01 Feb 2004
Pediatric Research

Volume: 55, P: 236-242
Publisher Correction: Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Tommi Vatanen
Damian R. Plichta
Ramnik J. Xavier
Amendments and Corrections05 Feb 2019
Nature Microbiology

Volume: 4, P: 545
Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children

Lauric A. Ferrat
Kendra Vehik
Roy Tamura
Amendments and Corrections14 Feb 2022
Nature Medicine

Volume: 28, P: 599
A combined risk score enhances prediction of type 1 diabetes among susceptible children

In a study of children with high genetic risk aged 2 years or older, a risk score integrating pancreatic islet autoantibodies, genetic factors and family history is highly predictive of type 1 diabetes in the subsequent 8 years.

Lauric A. Ferrat
Kendra Vehik
Roy Tamura
Research07 Aug 2020
Nature Medicine

Volume: 26, P: 1247-1255
Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes – Type 1 Diabetes Prediction and Prevention Study (DIPP)

Santosh Lamichhane
Linda Ahonen
Matej Oresic
ResearchOpen Access13 Jul 2018
Scientific Reports

Volume: 8, P: 1-12
Characterization and non-parametric modeling of the developing serum proteome during infancy and early childhood

Niina Lietzén
Lu Cheng
Riitta Lahesmaa
ResearchOpen Access12 Apr 2018
Scientific Reports

Volume: 8, P: 1-13
Author Correction: Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring

Jelena Štšepetova
Kärt Simre
Raivo Uibo
Amendments and CorrectionsOpen Access12 May 2022
Scientific Reports

Volume: 12, P: 1
Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes

Tove Grip
Thomas S. Dyrlund
Niklas Timby
Research04 Aug 2018
Pediatric Research

Volume: 84, P: 726-732
ConStrains identifies microbial strains in metagenomic datasets

Different bacterial strains in a metagenome are distinguished using a method that detects SNPs in conserved genes.

Chengwei Luo
Rob Knight
Dirk Gevers
Research07 Sept 2015
Nature Biotechnology

Volume: 33, P: 1045-1052
Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes

M. Karoliina Hirvonen
Niina Lietzén
Riitta Lahesmaa
ResearchOpen Access24 Sept 2023
Scientific Reports

Volume: 13, P: 1-11
Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring

Jelena Štšepetova
Kärt Simre
Raivo Uibo
ResearchOpen Access22 Apr 2022
Scientific Reports

Volume: 12, P: 1-12
A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes

Santosh Lamichhane
Linda Ahonen
Matej Orešič
ResearchOpen Access13 Nov 2018
Scientific Data

Volume: 5, P: 1-9
A Joint Modeling Approach for Childhood Meat, Fish and Egg Consumption and the Risk of Advanced Islet Autoimmunity

Essi Syrjälä
Jaakko Nevalainen
Suvi M. Virtanen
ResearchOpen Access23 May 2019
Scientific Reports

Volume: 9, P: 1-10
Development of T cell immunity to norovirus and rotavirus in children under five years of age

Maria Malm
Heikki Hyöty
Vesna Blazevic
ResearchOpen Access01 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes

Emilia Galli
Taina Härkönen
Päivi Lindholm
ResearchOpen Access30 Jun 2016
Scientific Reports

Volume: 6, P: 1-11
Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures

Anna Eurén
Kristian Lynch
Eric Triplett
ResearchOpen Access26 Oct 2024
Scientific Reports

Volume: 14, P: 1-14
Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study

Carina Törn
Xiang Liu
Eric W. Triplett
ResearchOpen Access16 Mar 2022
Scientific Reports

Volume: 12, P: 1-11
Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes

Ingrid Brænne
Suna Onengut-Gumuscu
Eric Triplett
ResearchOpen Access22 Nov 2021
Scientific Reports

Volume: 11, P: 1-13
Children’s erythrocyte fatty acids are associated with the risk of islet autoimmunity

Sari Niinistö
Iris Erlund
Eric Triplett
ResearchOpen Access11 Feb 2021
Scientific Reports

Volume: 11, P: 1-12
Toward defining the autoimmune microbiome for type 1 diabetes

Adriana Giongo
Kelsey A Gano
Eric W Triplett
Research08 Jul 2010
The ISME Journal

Volume: 5, P: 82-91
Metabolite-related dietary patterns and the development of islet autoimmunity

Randi K. Johnson
Lauren Vanderlinden
Eric Triplett
ResearchOpen Access15 Oct 2019
Scientific Reports

Volume: 9, P: 1-11
A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study

Mona Haghighi
Suzanne Bennett Johnson
Thomas Briese
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Carina Törn
Xiang Liu
Mari Åkerlund
ResearchOpen Access16 Jun 2016
Scientific Reports

Volume: 6, P: 1-10
Correction: Corrigendum: A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study

Mona Haghighi
Suzanne Bennett Johnson
Thomas Briese
Amendments and CorrectionsOpen Access02 May 2017
Scientific Reports

Volume: 7, P: 1

Search

Erythrocyte Insulin Binding in Preterm Newborn Infants

Nocturnal Release of Immunoreactive Growth Hormone-Releasing Hormone and Growth Hormone in Normal Children

Clinical Characteristics and Circulating Collagen and Laminin Metabolites in Insulin-Dependent Diabetic Children with Joint and Skin Manifestations

Metabolic and Hematologic Effects and Immune Complex Formation Related to Pertussis Immunization

Type 1 diabetes mellitus is a heterogeneous disease

Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Loss of β-cell mass — an acute event before T1DM presentation?

Soluble Adhesion Molecules in Preclinical Type 1 Diabetes

Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies

The role of the intestinal microbiota in type 1 diabetes mellitus

Centenarians have a diverse gut virome with the potential to modulate metabolism and promote healthy lifespan

Insulin Autoantibody Isotypes during the Prediabetic Process in Young Children with Increased Genetic Risk of Type 1 Diabetes

Publisher Correction: Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life

Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children

A combined risk score enhances prediction of type 1 diabetes among susceptible children

Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes – Type 1 Diabetes Prediction and Prevention Study (DIPP)

Characterization and non-parametric modeling of the developing serum proteome during infancy and early childhood

Author Correction: Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring

Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes

ConStrains identifies microbial strains in metagenomic datasets

Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes

Maternal breast milk microbiota and immune markers in relation to subsequent development of celiac disease in offspring

A longitudinal plasma lipidomics dataset from children who developed islet autoimmunity and type 1 diabetes

A Joint Modeling Approach for Childhood Meat, Fish and Egg Consumption and the Risk of Advanced Islet Autoimmunity

Development of T cell immunity to norovirus and rotavirus in children under five years of age

Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes

Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures

Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study

Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes

Children’s erythrocyte fatty acids are associated with the risk of islet autoimmunity

Toward defining the autoimmune microbiome for type 1 diabetes

Metabolite-related dietary patterns and the development of islet autoimmunity

A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

Correction: Corrigendum: A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study

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