Compounds that restore function to the cystic fibrosis–linked ΔF508 allele of CFTR can be classified on the basis of three corrector functions, representing different targets within the five domains of the channel protein. Combinations of individual compounds in the three classes can restore considerable function to the mutant channel.
- Tsukasa Okiyoneda
- Guido Veit
- Gergely L Lukacs
