Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–5 of 5 results
Advanced filters: Author: Miroslav Hejna Clear advanced filters
  • The chromatin remodeler Chd1 mediates hypertranscription in embryonic stem (ES) cells and has been shown to associate with genes transcribed by RNA Polymerase (Pol) I and II. Here the authors provide mechanistic insights into this process and reveal that Chd1 is involved in protecting genome integrity at promoter regions by preventing DNA break accumulation.

    • Aydan Bulut-Karslioglu
    • Hu Jin
    • Miguel Ramalho-Santos
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11
  • A high-throughput, chromosome-wide analysis of DNA looping reveals its contribution to the organization of chromatin, and provides insight into how nucleosomes are deposited and organised de novo.

    • Aakash Basu
    • Dmitriy G. Bobrovnikov
    • Taekjip Ha
    Research
    Nature
    Volume: 589, P: 462-467
  • MeCP2 is critical for proper brain development, and mutations in the gene encoding MeCP2 are responsible for several neurological disorders. Here, the authors show that the previously reported genome-wide preference of MeCP2 to methylated CpGs is in part due to MeCP2's affinity to GC-rich chromatin.

    • H. Tomas Rube
    • Wooje Lee
    • Qizhi Gong
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-12
  • Inhibition of mechanistic target of rapamycin (mTOR) suspends mouse blastocyst development and the cells remain ‘paused’ in a reversible pluripotent state, allowing prolonged culture.

    • Aydan Bulut-Karslioglu
    • Steffen Biechele
    • Miguel Ramalho-Santos
    Research
    Nature
    Volume: 540, P: 119-123