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Advanced filters: Author: Misaki Onozato Clear advanced filters

  • In a mouse model of intellectual disability, the chromatin remodeling protein ATR-X is shown to bind to G-quadruplex DNA structures and modulate target gene expression, which can be pharmacologically targeted to restore neuronal and cognitive phenotypes in these animals.

    • Norifumi Shioda
    • Yasushi Yabuki
    • Kohji Fukunaga
    Research
    Nature Medicine
    Volume: 24, P: 802-813