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Communications Biology (1)

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Enhancement of adult liver regeneration in mice through the hepsin-mediated epidermal growth factor receptor signaling pathway

Hepsin stimulates hepatocyte proliferation via the EGFR-Raf-MEK-ERK pathway to promote liver regeneration and recovery after partial hepatectomy without adverse effects, suggesting its therapeutic potential for liver resection and transplantation

Yu-Fei Tsai
Mo-Chu Fang
Shu-Wha Lin
ResearchOpen Access19 Dec 2024
Communications Biology

Volume: 7, P: 1-15

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Enhancement of adult liver regeneration in mice through the hepsin-mediated epidermal growth factor receptor signaling pathway

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