Highly active antiretroviral therapy is unable to eliminate HIV infection, because the virus persists in latently infected CD4+ T cells—a so-called virus reservoir. Rafick-Pierre Sekaly and his colleagues have shown that central memory CD4+ T cells and transitional memory CD4+ T cells are the main cellular reservoirs for HIV, and they suggest a mechanism that ensures the stability of this reservoir of virus.
- Nicolas Chomont
- Mohamed El-Far
- Rafick-Pierre Sékaly
