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Advanced filters: Author: Mohammad R. Inanlou Clear advanced filters

  • This study finds that the Hippo pathway is essential for gut epithelial regeneration and tumour initiation; the Hippo component Yap holds off differentiation of intestinal stem cells to Paneth cells to promote a survival and self-renewal regenerative program through activation of the Egfr pathway.

    • Alex Gregorieff
    • Yu Liu
    • Jeffrey L. Wrana
    Research
    Nature
    Volume: 526, P: 715-718