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Showing 1–4 of 4 results

Advanced filters: Author: Monika Tucholska Clear advanced filters

MSPLIT-DIA: sensitive peptide identification for data-independent acquisition

Jian Wang
Monika Tucholska
Nuno Bandeira
Correspondence09 Nov 2015
Nature Methods

Volume: 12, P: 1106-1108
Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

Several rearrangements of the MLL gene are associated with acute leukemia, including the fusion of MLL with a RAS effector protein, AF6. Here the authors show that the truncated AF6 can induce AF6-MLL dimerization and drive its oncogenic activity.

Matthew J. Smith
Elizabeth Ottoni
Mitsuhiko Ikura
ResearchOpen Access23 Oct 2017
Nature Communications

Volume: 8, P: 1-13
DIA-Umpire: comprehensive computational framework for data-independent acquisition proteomics

The computational workflow of DIA-Umpire allows untargeted peptide identificationdirectly from DIA (data-independent acquisition) proteomics data without dependence on a spectral library for data extraction

Chih-Chiang Tsou
Dmitry Avtonomov
Alexey I Nesvizhskii
Research19 Jan 2015
Nature Methods

Volume: 12, P: 258-264
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions

Müller et al. provide a comprehensive resource depicting cellular substrates, localization and interacting partners of RhoGEF and RhoGAP proteins regulating the canonical Rho family of GTPases.

Paul M. Müller
Juliane Rademacher
Oliver Rocks
Research23 Mar 2020
Nature Cell Biology

Volume: 22, P: 498-511