Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Moreno Wichert Clear advanced filters

  • A method to identify pairs of ligands that simultaneously bind to a target protein has been developed. The method uses two DNA-encoded chemical sub-libraries that self-assemble to form stable dual-display structures, and an encoding system that can be decoded by DNA sequencing and enables both ligands to be identified.

    • Moreno Wichert
    • Nikolaus Krall
    • Jörg Scheuermann
    Research
    Nature Chemistry
    Volume: 7, P: 241-249

  • This protocol describes an approach for screening DNA-encoded chemical libraries (DECLs) to identify molecules that bind to proteins of interest. After isolating binding library members, DNA barcodes are amplified and identified by high-throughput sequencing.

    • Willy Decurtins
    • Moreno Wichert
    • Jörg Scheuermann
    Protocols
    Nature Protocols
    Volume: 11, P: 764-780