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Showing 1–12 of 12 results
Advanced filters: Author: Morgan P. Hedges Clear advanced filters

  • The authors quantify the thermal tolerance of 305 populations from 61 taxa by meta-analysis. They reveal strong population-level differentiation in marine and intertidal taxa, but not terrestrial or freshwater taxa, and highlight the need to consider such variation in climate vulnerability predictions.

    • Matthew Sasaki
    • Jordanna M. Barley
    • Brian S. Cheng
    Research
    Nature Climate Change
    Volume: 12, P: 1175-1180

  • A quantum memory would enable storage and retrieval of a quantum state of light without corrupting the information it carries. Previous devices have had low efficiencies of less than 17 per cent, and used weak quantum states with an average photon number of around one. Now a solid-state quantum memory is described with an efficiency of up to 69 per cent, which performs better than a classical device for bright states of up to 500 photons.

    • Morgan P. Hedges
    • Jevon J. Longdell
    • Matthew J. Sellars
    Research
    Nature
    Volume: 465, P: 1052-1056

  • Radiation-induced high-grade gliomas (RIGs) are an incurable late complication of cranial radiation therapy. In the largest study to date, we report the results of DNA methylation profiling, RNA-Seq and genomic sequencing of 32 RIG tumors, and an in vitro drug screen in two RIG cell lines.

    • John DeSisto
    • John T. Lucas Jr.
    • Adam L. Green
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • An essential ingredient of future worldwide quantum communication is the generation of long-lived entangled quantum states; a coherence time of six hours is now reported for optically addressable nuclear spins in europium-doped yttrium orthosilicate.

    • Manjin Zhong
    • Morgan P. Hedges
    • Matthew J. Sellars
    Research
    Nature
    Volume: 517, P: 177-180

  • A meta-analysis of 17 cohorts of mitochondrial disease patients reveals that OxPhos defects are associated with signs of hypermetabolism. Experiments in patient-derived fibroblast show that mitochondrial OxPhos defects trigger hypermetabolism in a cell-autonomous manner and this is linked to accelerated telomere shortening and epigenetic aging.

    • Gabriel Sturm
    • Kalpita R. Karan
    • Martin Picard
    ResearchOpen Access
    Communications Biology
    Volume: 6, P: 1-22

  • We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new discoveries.

    • Daniel J. Benjamin
    • James O. Berger
    • Valen E. Johnson
    Comments & Opinion
    Nature Human Behaviour
    Volume: 2, P: 6-10

  • Ditches have many overlooked environmental and societal roles, including impact on biodiversity and pollution, and management strategies to enhance their multifunctional landscape-scale benefits are needed, according to a review of physical, biotic, chemical, and human factors.

    • Chelsea Clifford
    • Magdalena Bieroza
    • Mike Peacock
    ReviewsOpen Access
    Communications Earth & Environment
    Volume: 6, P: 1-16

  • Edmunds et al. examine how the adenosine receptor A2AR and the checkpoint molecule TIM3 suppress the killing of Renca tumors expressing hemagglutinin (HA) as a model neo-antigen by CL4 TCR transgenic T cells, which recognize an HA peptide presented by H-2Kd. The authors report that TIM3, which is upregulated on tumor-infiltrating CD8+ T cells after inhibition of A2AR, and A2AR impair the cytoskeletal polarization of the CL4 T cells.

    • Grace L. Edmunds
    • Carissa C. W. Wong
    • David J. Morgan
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-17