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Showing 1–11 of 11 results

Advanced filters: Author: Moshe Biton Clear advanced filters

Turbinate-homing IgA-secreting cells originate in the nasal lymphoid tissues

Nasal vaccination induces B cell expansion in the nasal-associated lymphoid tissues, followed by homing to the nasal turbinates and glandular acinar structures.

Jingjing Liu
Liat Stoler-Barak
Ziv Shulman
Research31 Jul 2024
Nature

Volume: 632, P: 637-646
Liver X receptor unlinks intestinal regeneration and tumorigenesis

Liver X receptor drives epithelial Areg-mediated intestinal regeneration, while preventing tumour growth through adaptive immune responses.

Srustidhar Das
S. Martina Parigi
Eduardo J. Villablanca
ResearchOpen Access20 Nov 2024
Nature

Volume: 637, P: 1198-1206
A single-cell survey of the small intestinal epithelium

Profiling of 53,193 individual epithelial cells from the mouse small intestine identifies previously unknown cell subtypes and corresponding gene markers, providing insight into gut homeostasis and response to pathogens.

Adam L. Haber
Moshe Biton
Aviv Regev
Research08 Nov 2017
Nature

Volume: 551, P: 333-339
SHDB-AF: a Japanese Holter ECG database of atrial fibrillation

Kenta Tsutsui
Shany Biton Brimer
Joachim A. Behar
ResearchOpen Access19 Mar 2025
Scientific Data

Volume: 12, P: 1-9
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes

Single-cell RNA sequencing analysis identifies cell types and lineages in airway epithelium, including the pulmonary ionocyte, a new cell type predominantly expressing the cystic fibrosis gene CFTR.

Daniel T. Montoro
Adam L. Haber
Jayaraj Rajagopal
Research01 Aug 2018
Nature

Volume: 560, P: 319-324
Epithelial microRNAs regulate gut mucosal immunity via epithelium–T cell crosstalk

Normal gut–immune system homeostasis requires interactions among epithelial cells, lymphocytes and host microflora. Ben-Neriah and colleagues show that defined microRNA expression in the gut mucosa is also important for maintaining gut integrity and homeostasis.

Moshe Biton
Avi Levin
Yinon Ben-Neriah
Research30 Jan 2011
Nature Immunology

Volume: 12, P: 239-246
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

Polygenic Priority Score (PoPS) prioritizes candidate effector genes at complex trait loci by integrating genome-wide association summary statistics with other data types. Combining PoPS with methods that leverage local genetic signals further improves the performance.

Elle M. Weeks
Jacob C. Ulirsch
Hilary K. Finucane
Research13 Jul 2023
Nature Genetics

Volume: 55, P: 1267-1276
Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D

The mechanisms controlling expression of the stress-induced NKG2D ligands MICA and MICB are not fully understood. Mandelboim and colleagues suggest that microRNAs maintain low MICA and MICB expression in the absence of cell stress.

Noam Stern-Ginossar
Chamutal Gur
Ofer Mandelboim
Research01 Aug 2008
Nature Immunology

Volume: 9, P: 1065-1073
Generation of specialized blood vessels via lymphatic transdifferentiation

A study of zebrafish identifies an innate mechanism of blood vessel formation through the transdifferentiation of lymphatic endothelial cells, and provides in vivo evidence for a link between cell ontogeny and functionality in endothelial cells.

Rudra N. Das
Yaara Tevet
Karina Yaniv
Research25 May 2022
Nature

Volume: 606, P: 570-575
The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic

In two mouse models of intestinal cancer, mutant p53 has an oncogenic effect in the distal gut but a tumour-suppressive effect in the proximal gut, and these opposing properties are determined by the gut microbiome.

Eliran Kadosh
Irit Snir-Alkalay
Yinon Ben-Neriah
Research29 Jul 2020
Nature

Volume: 586, P: 133-138
Longitudinal single-cell data informs deterministic modelling of inflammatory bowel disease

Christoph Kilian
Hanna Ulrich
Lorenz Adlung
ResearchOpen Access24 Jun 2024
npj Systems Biology and Applications

Volume: 10, P: 1-9