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Showing 1–6 of 6 results
Advanced filters: Author: Mostafa Ellabaan Clear advanced filters

  • Antibiotic resistance spreads among bacteria through horizontal transfer of antibiotic resistance genes (ARGs). Here, Ellabaan et al. use a statistical approach to identify putative mobilisation elements and other features associated with ARG transfer among bacterial clades to predict the potential future dissemination of known ARGs.

    • Mostafa M. H. Ellabaan
    • Christian Munck
    • Morten O. A. Sommer
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • The authors study the interactions between chromosomal mutations and horizontally acquired genes in the evolution of antibiotic resistance in experimental evolution assays. They identify constraints that may allow better prediction and control of antibiotic resistance evolution.

    • Andreas Porse
    • Leonie J. Jahn
    • Morten O. A. Sommer
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-9

  • Some antibiotic resistance genes found in pathogenic bacteria might derive from antibiotic-producing actinobacteria. Here, Jianget al. provide bioinformatic and experimental evidence supporting this hypothesis, and propose a specific mechanism for the transfer of these genes between bacterial phyla.

    • Xinglin Jiang
    • Mostafa M. Hashim Ellabaan
    • Sang Yup Lee
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7

  • Wastewater treatment plants (WWTPs) are thought to play a central role in the dissemination of antibiotic resistance genes. Here, the authors identify novel antibiotic resistance genes in WWTPs and show that only a few of the most abundant resistance genes are found outside the WWTP environment.

    • Christian Munck
    • Mads Albertsen
    • Morten O. A. Sommer
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-10

  • Sequence composition is thought to be a major factor governing the functionality of horizontally transferred genes. In contrast, Porse et al. show that phylogenetic origin, and the type of resistance mechanism, are major factors affecting the functionality of horizontally transferred antibiotic resistance genes.

    • Andreas Porse
    • Thea S. Schou
    • Morten O. A. Sommer
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11