Awareness of IgG4-related disease, which shares many clinical, and potentially pathogenetic, similarities with certain rheumatic disorders, is increasing worldwide. This Review provides an overview of this disease entity, with particular focus on pathogenesis, clinical features, diagnosis and treatment, for the benefit of rheumatologists, who are increasingly likely to be involved in the diagnosis and management of patients with IgG4-related disorders.
- Motohisa Yamamoto
- Hiroki Takahashi
- Yasuhisa Shinomura