Nature Search

Behaviour of octopus rhodopsin and its photoproducts at very low temperatures

Motoyuki Tsuda
Fumio Tokunaga
Laura Eisenstein
Research02 Oct 1980
Nature

Volume: 287, P: 461-462
Light isomerizes the chromophore of bacteriorhodopsin

Motoyuki Tsuda
Moira Glaccum
Thomas G. Ebrey
Research01 Sept 1980
Nature

Volume: 287, P: 351-353
Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer

Using pancreatic organoids and genetic mouse models, Antonucci et al. show that cellular stress activates an NRF2–EZH2 epigenetic axis leading to metabolic reprogramming and subsequent malignant transformation of KRAS-mutant benign lesions.

Laura Antonucci
Na Li
Michael Karin
Research30 Jun 2025
Nature Cancer

Volume: 6, P: 1263-1282
Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer

Sears and colleagues found that ongoing replication stress pathways and T cell clonal responses differentiate liver and lung recurrence and are associated with different clinical outcomes in the context of pancreatic ductal adenocarcinoma.

Jason M. Link
Jennifer R. Eng
Rosalie C. Sears
ResearchOpen Access09 Jan 2025
Nature Cancer

Volume: 6, P: 123-144
THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer

Thrombospondin-1 (THBS1) is a matricellular protein highly expressed in inflammatory processes, including cancer. Here the authors show that bone-marrow derived monocyte-like cells are the primary source of THBS1 in colorectal cancer, associated with mesenchymal characteristics, immunosuppression and a poor prognosis.

Mayuki Omatsu
Yuki Nakanishi
Hiroshi Seno
ResearchOpen Access25 Sept 2023
Nature Communications

Volume: 14, P: 1-19
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

Edgar A Otto
Bart Loeys
Friedhelm Hildebrandt
Research20 Feb 2005
Nature Genetics

Volume: 37, P: 282-288
The pre-vertebrate origins of neurogenic placodes

A study showing that tunicates possess a proto-placodal ectoderm that produces neurons with dual neurosecretory and chemosensory function, which may represent the ancestral origin of placode-derived neurons in vertebrates.

Philip Barron Abitua
T. Blair Gainous
Michael Levine
Research10 Aug 2015
Nature

Volume: 524, P: 462-465
The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

John A Sayer
Edgar A Otto
Friedhelm Hildebrandt
Research07 May 2006
Nature Genetics

Volume: 38, P: 674-681
Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway

Osamu Araki
Motoyuki Tsuda
Hiroshi Seno
Research18 May 2023
Oncogene

Volume: 42, P: 2139-2152
Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice

Yojiro Sakuma
Yuzo Kodama
Hiroshi Seno
ResearchOpen Access11 Jun 2018
Scientific Reports

Volume: 8, P: 1-13
Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis

Yoshihiro Nishikawa
Yuzo Kodama
Hiroshi Seno
Research31 Jan 2019
Oncogene

Volume: 38, P: 4283-4296

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Behaviour of octopus rhodopsin and its photoproducts at very low temperatures

Light isomerizes the chromophore of bacteriorhodopsin

Self-amplifying NRF2–EZH2 epigenetic loop converts KRAS-initiated progenitors to invasive pancreatic cancer

Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer

THBS1-producing tumor-infiltrating monocyte-like cells contribute to immunosuppression and metastasis in colorectal cancer

Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin

The pre-vertebrate origins of neurogenic placodes

The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

Brg1 controls stemness and metastasis of pancreatic cancer through regulating hypoxia pathway

Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice

Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis

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