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Advanced filters: Author: Musadiq A. Bhat Clear advanced filters

Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release

Nociceptin is an opioid peptide regulating important brain functions, including motivation and 2stress responses. Here, the authors develop and validate a genetically encoded sensor as a tool for high-resolution detection of endogenous nociceptin in living animals.

Xuehan Zhou
Carrie Stine
Tommaso Patriarchi
ResearchOpen Access25 Jun 2024
Nature Communications

Volume: 15, P: 1-20
Sensitive multicolor indicators for monitoring norepinephrine in vivo

Red and green genetically encoded indicators for norepinephrine have been developed and employed to monitor norepinephrine during locomotion and reward behavior in mice. The strategy used for generating these indicators also produced indicators for other neuromodulators.

Zacharoula Kagiampaki
Valentin Rohner
Tommaso Patriarchi
Research20 Jul 2023
Nature Methods

Volume: 20, P: 1426-1436
The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABA_B receptors under ischemic conditions by inhibiting fast receptor recycling

Musadiq A. Bhat
Mohammad Hleihil
Dietmar Benke
ResearchOpen Access08 Jan 2025
Scientific Reports

Volume: 15, P: 1-20