Here, using ex-vivo human adult cortical tissue and a mouse model, the authors investigate the functional consequences of Zika virus (ZIKV) infection in the adult brain, and show that ZIKV causes synapse damage and altered brain function that impacts cognition via activation of innate and inflammatory factors.
- Claudia P. Figueiredo
- Fernanda G. Q. Barros-Aragão
- Sergio T. Ferreira
