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Showing 1–8 of 8 results

Advanced filters: Author: N Issaeva Clear advanced filters

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

Vladimir J.N. Bykov
Natalia Issaeva
Galina Selivanova
Research01 Mar 2002
Nature Medicine

Volume: 8, P: 282-288
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

One of two papers linking oncogene-induced senescence and the DNA damage response. Activated oncogenes can cause aberrant DNA replication and thereby DNA damage, which leads to cellular senescence. This response can block tumour progression, but is often disabled by further alterations.

Jirina Bartkova
Nousin Rezaei
Vassilis G. Gorgoulis
Research01 Nov 2006
Nature

Volume: 444, P: 633-637
Small molecule MIRA-1 induces in vitro and in vivo anti-myeloma activity and synergizes with current anti-myeloma agents

M N Saha
Y Chen
H Chang
ResearchOpen Access01 Apr 2014
British Journal of Cancer

Volume: 110, P: 2224-2231
Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner

J J Wamsley
C Gary
W G Yarbrough
ResearchOpen Access10 Apr 2017
Oncogenesis

Volume: 6, P: e314
PRIMA-1^MET synergizes with cisplatin to induce tumor cell apoptosis

Vladimir J N Bykov
Nicole Zache
Klas G Wiman
Research28 Feb 2005
Oncogene

Volume: 24, P: 3484-3491
The role of PARP in DNA repair and its therapeutic exploitation

M Javle
N J Curtin
ReviewsOpen Access11 Oct 2011
British Journal of Cancer

Volume: 105, P: 1114-1122
TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

S V Ivanov
A Panaccione
W G Yarbrough
Research01 Oct 2012
Oncogene

Volume: 32, P: 3698-3710
ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis

Y Shi
F Nikulenkov
G Selivanova
ResearchOpen Access10 Jan 2014
Cell Death & Differentiation

Volume: 21, P: 612-623