Isakson et al. report a genetically engineered minipig model of Neurofibromatosis Type 1 (NF1) that exhibits clinical hallmarks of the disease, including neurofibromas and optic pathway glioma. This model may expedite the development of imaging methods, biomarkers, and therapies for NF1 patients.
- Sara H. Isakson
- Anthony E. Rizzardi
- Adrienne L. Watson