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Showing 1–50 of 91 results

Advanced filters: Author: N Yasui Clear advanced filters

Flower movement induced by weather-dependent tropism satisfies attraction and protection

Flowers have antagonistic demands for reproductive success, that is, pollinator attraction and flower protection. Here, the authors report that the weather-dependent tropism of flower pedicels functions to satisfy the antagonistic reproductive demands.

Akari Shibata
Genki Yumoto
Hiroshi Kudoh
ResearchOpen Access03 May 2025
Nature Communications

Volume: 16, P: 1-13
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway

Diane Watling
Dmitry Guschin
lan M. Kerr
Research11 Nov 1993
Nature

Volume: 366, P: 166-170
Super-assembly of ER-phagy receptor Atg40 induces local ER remodeling at contacts with forming autophagosomal membranes

The ER is subject to autophagy (ER-phagy) for turnover, with Atg40 acting as a receptor to sequester ER with Atg8 in autophagosomes. Here, the authors show that Atg40 is clustered by interaction with Atg8 to generate local membrane curvature and promote autophagosome packing.

Keisuke Mochida
Akinori Yamasaki
Hitoshi Nakatogawa
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-14
Phase-locking to a free-space terahertz comb for metrological-grade terahertz lasers

Frequency comb synthesizers are important for metrology, but they have been difficult to use as frequency rulers in the terahertz region due to their low power. Consolinoet al. phase-lock a quantum cascade laser to a free-space-propagating terahertz comb, demonstrating that they can overcome this limitation.

L. Consolino
A. Taschin
P. De Natale
Research04 Sept 2012
Nature Communications

Volume: 3, P: 1-5
In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds

Mice expressing humanized mutant tau exhibit synaptic loss and behavioral abnormalities in the absence of abnormal tau conformers, suggesting that hyperphosphorylated tau can be pathological, at least in tauopathies caused by tau isoform imbalance.

Naoto Watamura
Martha S. Foiani
Takaomi C. Saido
ResearchOpen Access24 Dec 2024
Nature Neuroscience

Volume: 28, P: 293-307
Structural basis of starvation-induced assembly of the autophagy initiation complex

Autophagy initiates with the assembly of a preautophagosomal structure (PAS), triggered by the yeast Atg1 complex. Ohsumi, Noda and colleagues present the crystal structures of Atg13–Atg1 and Atg13–Atg17, revealing how starvation-induced dephosphorylation of Atg13 triggers formationof the Atg1 complex and PAS assembly.

Yuko Fujioka
Sho W Suzuki
Nobuo N Noda
Research04 May 2014
Nature Structural & Molecular Biology

Volume: 21, P: 513-521
Origin of the West Philippine Basin

D. KARIG
J. C. INGLE jun.
H. YI LING
Research21 Dec 1973
Nature

Volume: 246, P: 458-461
Evolution from covalent conjugation to non-covalent interaction in the ubiquitin-like ATG12 system

ATG12 and ATG5 are covalently conjugated during autophagy. Exceptions are now uncovered: in Plasmodium and Toxoplasma species and in yeast Komagataella phaffii (previously Pichia pastoris), ATG12 and ATG5 form a non-covalent yet functional complex.

Yu Pang
Hayashi Yamamoto
Noboru Mizushima
Research25 Mar 2019
Nature Structural & Molecular Biology

Volume: 26, P: 289-296
Lack of Expression of the Epstein-Barr Virus (EBV) Gene Products, EBERs, EBNA1, LMP1, and LMP2A, in Breast Cancer Cells

C G Deshpande
S Badve
R Longnecker
Research01 Sept 2002
Laboratory Investigation

Volume: 82, P: 1193-1199
Seasonal switching of integrated leaf senescence controls in an evergreen perennial Arabidopsis

A study of perennial Arabidopsis in its natural habitat revealed a seasonal switch in leaf senescence control that optimizes resource production, storage, and translocation, making the evergreen strategy adaptively relevant in seasonal environments.

Genki Yumoto
Haruki Nishio
Hiroshi Kudoh
ResearchOpen Access07 Jun 2024
Nature Communications

Volume: 15, P: 1-16
Prognostic significance of cyclin E and p53 protein overexpression in carcinoma of the renal pelvis and ureter

M Furihata
Y Ohtsuki
M Kuwahara
Research01 Mar 1998
British Journal of Cancer

Volume: 77, P: 783-788
Isotopic Dating and Palaeomagnetic Polarity in the Faeroe Islands

D. H. TARLING
N. H. GALE
Research15 Jun 1968
Nature

Volume: 218, P: 1043-1044
Diamond nanowires, a new approach towards next generation electrochemical gene sensor platforms

Nianjun Yang
Hiroshi Uetsuka
Christoph Nebel
ResearchOpen Access24 Mar 2008
Nature Precedings

P: 1
Atg2 mediates direct lipid transfer between membranes for autophagosome formation

Structural and biochemical data suggest that the essential autophagy protein Atg2 acts as a lipid-transfer protein that supplies phospholipids from the source organelle (especially the ER) to the isolation membranes (IMs) for autophagosome formation.

Takuo Osawa
Tetsuya Kotani
Nobuo N. Noda
Research25 Mar 2019
Nature Structural & Molecular Biology

Volume: 26, P: 281-288
Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck

J Ishitoya
M Toriyama
T Yamamoto
Research01 Apr 1989
British Journal of Cancer

Volume: 59, P: 559-562
A novel type X collagen gene mutation (G595R) associated with Schmid-type metaphyseal chondrodysplasia

Y. Matsui
N. Yasui
T. Ochi
Research01 Mar 2000
Journal of Human Genetics

Volume: 45, P: 105-108
Trigonelline is an NAD⁺ precursor that improves muscle function during ageing and is reduced in human sarcopenia

Trigonelline is identified as a human metabolite that can be used for NAD⁺ synthesis and is shown to improve muscle function in aged worms and mice.

Mathieu Membrez
Eugenia Migliavacca
Jerome N. Feige
ResearchOpen Access19 Mar 2024
Nature Metabolism

Volume: 6, P: 433-447
Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice

Y Kitadai
Y Takahashi
E Tahara
ResearchOpen Access24 Sept 1999
British Journal of Cancer

Volume: 81, P: 647-653
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Breast cancer: trends in international incidence in men and women

E Kreiter
A Richardson
Y Yasui
ResearchOpen Access11 Feb 2014
British Journal of Cancer

Volume: 110, P: 1891-1897
Coexpression of cdk2/cdc2 and retinoblastoma gene products in colorectal cancer

H Yamamoto
T Monden
M Monden
Research01 Jun 1995
British Journal of Cancer

Volume: 71, P: 1231-1236
Detection of telomerase activity in peritoneal lavage fluid from patients with gastric cancer using immunomagnetic beads

N Mori
M Oka
K Hirose
ResearchOpen Access19 Sept 2000
British Journal of Cancer

Volume: 83, P: 1026-1032
Differential patterns of placental and epithelial cadherin expression in basal cell carcinoma and in the epidermis overlying tumours

A Pizarro
C Gamallo
F Contreras
Research01 Aug 1995
British Journal of Cancer

Volume: 72, P: 327-332
Can ABCF2 protein expression predict the prognosis of uterine cancer?

S Nishimura
H Tsuda
D Aoki
ResearchOpen Access11 Nov 2008
British Journal of Cancer

Volume: 99, P: 1651-1655
Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Using more than 100 independent iPSC lines derived from patients with Alzheimer’s disease, the authors discovered loci associated with the neuronal production of amyloid β and confirmed their influence using RNA interference.

Takayuki Kondo
Norikazu Hara
Haruhisa Inoue
Research17 Feb 2022
Nature Aging

Volume: 2, P: 125-139
Head and backbone of the Early Cambrian vertebrate Haikouichthys

D.-G. Shu
S. Conway Morris
H.-Q. Liu
Research30 Jan 2003
Nature

Volume: 421, P: 526-529
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancer

P P Aung
N Oue
W Yasui
Research05 Dec 2005
Oncogene

Volume: 25, P: 2546-2557
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor

L Damstrup
B Rude Voldborg
H Skovgaard Poulsen
Research01 Sept 1998
British Journal of Cancer

Volume: 78, P: 631-640
Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapy

Y Mitani
N Oue
W Yasui
Research22 Jan 2007
Oncogene

Volume: 26, P: 4383-4393
Structure, lipid scrambling activity and role in autophagosome formation of ATG9A

Cryo-EM analyses together with liposome and cellular assays reveal that human ATG9A forms a trimer that mediates phospholipid flipping and promotes autophagosome membrane expansion.

Shintaro Maeda
Hayashi Yamamoto
Takanori Otomo
Research26 Oct 2020
Nature Structural & Molecular Biology

Volume: 27, P: 1194-1201
Proliferation defects and genome instability in cells lacking Cul4A

D Kopanja
T Stoyanova
P Raychaudhuri
Research11 May 2009
Oncogene

Volume: 28, P: 2456-2465
A glutamine sensor that directly activates TORC1

Tanigawa et al. investigate the role of Pib2, a vacuolar protein, in the glutamine-dependent upstream regulation of TORC1 in budding yeast. Their study reveals that Pib2 plays dual roles as a glutamine sensor and a direct TORC1 activator, a finding useful for the community working on TORC1 upstream regulation.

Mirai Tanigawa
Katsuyoshi Yamamoto
Tatsuya Maeda
ResearchOpen Access17 Sept 2021
Communications Biology

Volume: 4, P: 1-11
Defective expression of polarity protein PAR-3 gene (PARD3) in esophageal squamous cell carcinoma

K Zen
K Yasui
T Yoshikawa
Research08 Jun 2009
Oncogene

Volume: 28, P: 2910-2918
E-cadherin and α-, β- and γ-catenin expression in prostate cancers: correlation with tumour invasion

N Morita
H Uemura
Y Hiasa
ResearchOpen Access12 Mar 1999
British Journal of Cancer

Volume: 79, P: 1879-1883
Face-selective tungstate ions drive zinc oxide nanowire growth direction and dopant incorporation

Controlling the growth processes of nanowires is vital for tailoring their properties. Here, the presence of tungstate ions on specific surface planes of zinc oxide nanowires causes nanowire growth and chemical doping along specific crystal planes.

Jiangyang Liu
Kazuki Nagashima
Takeshi Yanagida
ResearchOpen Access13 Aug 2020
Communications Materials

Volume: 1, P: 1-10
Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro

E Ohmura
K Wakai
RK Robins
Research01 Feb 1993
British Journal of Cancer

Volume: 67, P: 279-283
Allele associations reveal four prominent haplotypes at the human interleukin-6 (IL-6) locus

N Jordanides
J Eskdale
G Gallagher
Research13 Oct 2000
Genes & Immunity

Volume: 1, P: 451-455
High-dose chemotherapy for high-risk retinoblastoma: clinical course and outcome of 14 cases in the National Cancer Center, Japan

N Yasui
H Kawamoto
S Suzuki
Research01 Dec 2014
Bone Marrow Transplantation

Volume: 50, P: 221-224
IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A

N. Sugimoto
I. Imoto
J. Inazawa
Research01 Jan 2001
Journal of Human Genetics

Volume: 46, P: 21-25
A novel missense mutation of the tissue-nonspecific alkaline phosphatase gene detected in a patient with hypophosphatasia

N. Sugimoto
Sadahiko Iwamoto
Eiji Kajii
Research01 Sept 1998
Journal of Human Genetics

Volume: 43, P: 160-164
Immunohistochemical localization of chondroitin sulphate and dermatan sulphate proteoglycans in tumour tissues

T Fukatsu
M Sobue
J Takeuchi
Research01 Jan 1988
British Journal of Cancer

Volume: 57, P: 74-78
Antimyeloma activity of two novel N-substituted and tetraflourinated thalidomide analogs

S Kumar
N Raje
K C Anderson
Research28 Apr 2005
Leukemia

Volume: 19, P: 1253-1261
The influence of invasive growth pattern and microvessel density on prognosis in colorectal cancer and colorectal liver metastases

R Rajaganeshan
R Prasad
D G Jayne
ResearchOpen Access13 Mar 2007
British Journal of Cancer

Volume: 96, P: 1112-1117
Risk of breast cancer according to clinicopathologic features among long-term survivors of Hodgkin's lymphoma treated with radiotherapy

G M Dores
W F Anderson
R E Curtis
ResearchOpen Access14 Sept 2010
British Journal of Cancer

Volume: 103, P: 1081-1084
Increased large-scale inter-network connectivity in relation to impulsivity in Parkinson’s disease

Jinsoo Koh
Yoshiki Kaneoke
Hidefumi Ito
ResearchOpen Access10 Jul 2020
Scientific Reports

Volume: 10, P: 1-9
Close-to-lesion transbronchial biopsy: a novel technique to improve suitability of specimens for genetic testing in patients with peripheral pulmonary lesions

Yoichi Nishii
Tadashi Sakaguchi
Osamu Hataji
ResearchOpen Access07 Sept 2023
Scientific Reports

Volume: 13, P: 1-11
FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect

K Asada
T Ando
T Ushijima
Research11 Jun 2012
Oncogene

Volume: 32, P: 2140-2149
Kinetics of plasma cytokines after hematopoietic stem cell transplantation from unrelated donors: the ratio of plasma IL-10/sTNFR level as a potential prognostic marker in severe acute graft-versus-host disease

N Sakata
M Yasui
K Kawa
Research06 Jul 2001
Bone Marrow Transplantation

Volume: 27, P: 1153-1161
Osteopontin is a marker for cancer aggressiveness and patient survival

G F Weber
G S Lett
N C Haubein
ResearchOpen Access07 Sept 2010
British Journal of Cancer

Volume: 103, P: 861-869

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