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  • Post-lactational involution in the mammary gland is shown to be accomplished by a lysosome-mediated cell death pathway. This pathway is independent of the executioner caspases 3, 6 and 7, and instead relies on Stat3-mediated upregulation of cathepsins.

    • Peter A. Kreuzaler
    • Anna D. Staniszewska
    • Christine J. Watson
    Research
    Nature Cell Biology
    Volume: 13, P: 303-309