Nature Search

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Raymond K. Walters
Renato Polimanti
Arpana Agrawal
Research26 Nov 2018
Nature Neuroscience

Volume: 21, P: 1656-1669
Peptide ligand-induced conformation and surface expression of the L^d class I MHC molecule

Wen-Rong Lie
Nancy B. Myers
Ted. H. Hansen
Research29 Mar 1990
Nature

Volume: 344, P: 439-441
Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

Rolf Renne
Weidong Zhong
Don Ganem
Research01 Mar 1996
Nature Medicine

Volume: 2, P: 342-346
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes

In 653,790 individuals, this multi-ancestral meta-analysis of tobacco use disorder finds 461 potential risk genes and hundreds of associations with health outcomes, showcasing the utility of electronic health records for genetic research.

Sylvanus Toikumo
Mariela V. Jennings
Sandra Sanchez-Roige
Research17 Apr 2024
Nature Human Behaviour

Volume: 8, P: 1177-1193
Nf1 deficiency causes Ras-Dediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

David A. Largaespada
Camilynn I. Brannan
Neal G. Copeland
Research01 Feb 1996
Nature Genetics

Volume: 12, P: 137-143
Zinc Supplementation Selectively Decreases Fetal Hepatocyte DNA Synthesis and Insulin-Like Growth Factor II Gene Expression in Primary Culture

Susan F Townsend
Karen K Briggs
K Michael Hambidge
Research01 Apr 1994
Pediatric Research

Volume: 35, P: 404-408
lonomycin-regulated phosphorylation of the myeloid calcium-binding protein p14

Jonathan Edgeworth
Paul Freemont
Nancy Hogg
Research09 Nov 1989
Nature

Volume: 342, P: 189-192
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Depression is correlated with many brain-related traits. Here, Shen et al. perform phenome-wide association studies of a depression polygenic risk score (PRS) and find associations with 51 behavioural and 26 neuroimaging traits which are further followed up on using Mendelian randomization and mediation analyses.

Xueyi Shen
David M. Howard
Andrew M. McIntosh
ResearchOpen Access08 May 2020
Nature Communications

Volume: 11, P: 1-16
C. elegans ageing is accelerated by a self-destructive reproductive programme

Caenorhabditis elegans is used as a model species to investigate ageing, yet has a very high degree of plasticity in lifespan. This study argues that ageing in C. elegans is driven by suicidal reproductive effort, unlike many other organisms.

Carina C. Kern
Shivangi Srivastava
David Gems
ResearchOpen Access20 Jul 2023
Nature Communications

Volume: 14, P: 1-12
Effects of Diet and Behavior Therapy on Social and Motor Behavior of Retarded Phenylketonuric Adults: An Experimental Analysis

David Marholin II
Robert E Pohl III
Edwin H Kolodny
Research01 Mar 1978
Pediatric Research

Volume: 12, P: 179-187
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

A genetic study identifies hundreds of loci associated with risk tolerance and risky behaviors, finds evidence of substantial shared genetic influences across these phenotypes, and implicates genes involved in neurotransmission.

Richard Karlsson Linnér
Pietro Biroli
Jonathan P. Beauchamp
Research14 Jan 2019
Nature Genetics

Volume: 51, P: 245-257
One-quarter of freshwater fauna threatened with extinction

A global multi-taxon extinction risk assessment of freshwater fauna for The IUCN Red List of Threatened Species finds one-quarter of species to be at high risk of extinction.

Catherine A. Sayer
Eresha Fernando
William R. T. Darwall
ResearchOpen Access08 Jan 2025
Nature

Volume: 638, P: 138-145
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Jonathan R. I. Coleman
Wouter J. Peyrot
Gerome Breen
Research23 Jan 2020
Molecular Psychiatry

Volume: 25, P: 1430-1446
Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer

Jennifer L. Guerriero
Jia-Ren Lin
Sandro Santagata
ResearchOpen Access02 Jan 2024
npj Breast Cancer

Volume: 10, P: 1-22
Morphological evolution of creek networks in 10 restored coastal wetlands in the UK

C. Chirol
I. D. Haigh
S. L. Gallop
ResearchOpen Access01 Apr 2022
Scientific Data

Volume: 9, P: 1-16
A dataset of acoustic measurements from soundscapes collected worldwide during the COVID-19 pandemic

Samuel Challéat
Nicolas Farrugia
Vera Zina
ResearchOpen Access27 Aug 2024
Scientific Data

Volume: 11, P: 1-16

Search

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Peptide ligand-induced conformation and surface expression of the L^d class I MHC molecule

Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes

Nf1 deficiency causes Ras-Dediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia

Zinc Supplementation Selectively Decreases Fetal Hepatocyte DNA Synthesis and Insulin-Like Growth Factor II Gene Expression in Primary Culture

lonomycin-regulated phosphorylation of the myeloid calcium-binding protein p14

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

C. elegans ageing is accelerated by a self-destructive reproductive programme

Effects of Diet and Behavior Therapy on Social and Motor Behavior of Retarded Phenylketonuric Adults: An Experimental Analysis

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

One-quarter of freshwater fauna threatened with extinction

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

Qualification of a multiplexed tissue imaging assay and detection of novel patterns of HER2 heterogeneity in breast cancer

Morphological evolution of creek networks in 10 restored coastal wetlands in the UK

A dataset of acoustic measurements from soundscapes collected worldwide during the COVID-19 pandemic

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