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Showing 1–22 of 22 results

Advanced filters: Author: Nancy R. Manley Clear advanced filters

MiCASA is a new method for quantifying cellular organization

There are few methods available that can quantify relationships between cell types in tissue images. Here the authors present a quantitative method to evaluate cellular organization, validated in the mouse thymus and spinal cord, called Multitaper Circularly Averaged Spectral Analysis (MiCASA).

Andrew Sornborger
Jie Li
Nancy R. Manley
ResearchOpen Access30 May 2017
Nature Communications

Volume: 8, P: 1-10
Global hotspots of mycorrhizal fungal richness are poorly protected

Machine-learning algorithms trained on 25,000 geolocated soil samples are used to create high-resolution global maps of mycorrhizal fungi, revealing that less than 10% of their biodiversity hotspots are in protected areas.

Michael E. Van Nuland
Colin Averill
Johan van den Hoogen
ResearchOpen Access23 Jul 2025
Nature

Volume: 645, P: 414-422
Transdifferentiation of parathyroid cells into cervical thymi promotes atypical T-cell development

Cervical thymi are secondary sites of T-cell development in mice. Here, the authors investigate previously unknown origin of cervical thymi and show that they develop as a by-product of the normal separation of thymic and parathyroid tissue.

Jie Li
Zhijie Liu
Nancy R. Manley
Research17 Dec 2013
Nature Communications

Volume: 4, P: 1-8
Correction: Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued

Erika L. F. Holzbaur,
James A. Hammarback
Richard B. Vallee
Amendments and Corrections17 Dec 1992
Nature

Volume: 360, P: 695
Thymic mimetic cells function beyond self-tolerance

Multiomic analyses of mouse thymic epithelial cells identify several unconventional subsets that are mimetics of various populations of terminally differentiated parenchymal cells and provide insights into their development, molecular features and function.

Tal Givony
Dena Leshkowitz
Jakub Abramson
Research06 Sept 2023
Nature

Volume: 622, P: 164-172
Sculpting of the spliceosomal branch site recognition motif by a conserved pseudouridine

Meredith I. Newby
Nancy L. Greenbaum
Research11 Nov 2002
Nature Structural Biology

Volume: 9, P: 958-965
Age-related epithelial defects limit thymic function and regeneration

Here the authors identify age-associated changes in the epithelial cell compartment of the thymus that form high-density nonproductive microenvironmental niches that contribute toward thymic involution and inhibit its repair following injury.

Anastasia I. Kousa
Lorenz Jahn
Jarrod A. Dudakov
ResearchOpen Access07 Aug 2024
Nature Immunology

Volume: 25, P: 1593-1606
A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

This Registered Report presents evidence from 87 countries and regions showing that brief emotion-regulation interventions consistently reduced negative emotions and increased positive emotions during the COVID-19 pandemic.

Ke Wang
Amit Goldenberg
Hannah Moshontz
Research02 Aug 2021
Nature Human Behaviour

Volume: 5, P: 1089-1110
Developing a new paradigm for thymus organogenesis

C. Clare Blackburn
Nancy R. Manley
Reviews01 Apr 2004
Nature Reviews Immunology

Volume: 4, P: 278-289
Serum metabolome associated with severity of acute traumatic brain injury

Traumatic brain injury is associated with changes to the metabolome. Here the authors show that acute traumatic brain injury has distinctive serum metabolic patterns which may suggest protective changes of systemic lipid metabolism aiming to maintain lipid homeostasis in the brain.

Ilias Thomas
Alex M. Dickens
Tommaso Zoerle
ResearchOpen Access10 May 2022
Nature Communications

Volume: 13, P: 1-15
A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation

Dong-ming Su
Samuel Navarre
Nancy R Manley
Research05 Oct 2003
Nature Immunology

Volume: 4, P: 1128-1135
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Functional evidence for a single endodermal origin for the thymic epithelium

Julie Gordon
Valerie A Wilson
C Clare Blackburn
Research18 Apr 2004
Nature Immunology

Volume: 5, P: 546-553
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Association of day-of-injury plasma glial fibrillary acidic protein concentration and six-month posttraumatic stress disorder in patients with mild traumatic brain injury

Jacqueline R. Kulbe
Sonia Jain
Ross Zafonte
ResearchOpen Access18 Jun 2022
Neuropsychopharmacology

Volume: 47, P: 2300-2308
Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury

Murray B. Stein
Sonia Jain
Ross Zafonte
ResearchOpen Access25 Jan 2023
Translational Psychiatry

Volume: 13, P: 1-6
An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts

Generation of functional T-cells for therapeutic purposes requires a thymic epithelium. Blackburn and colleagues show that FOXN1 expression in fibroblasts triggers the formation of functional thymic epithelial cells that support T-cell differentiation from haematopoietic progenitors.

Nicholas Bredenkamp
Svetlana Ulyanchenko
Catherine Clare Blackburn
Research24 Aug 2014
Nature Cell Biology

Volume: 16, P: 902-908
Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

Ke Wang
Amit Goldenberg
Hannah Moshontz
Amendments and Corrections24 Aug 2022
Nature Human Behaviour

Volume: 6, P: 1318-1319
Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury

Fabian Bockhop
Marina Zeldovich
Tommaso Zoerle
ResearchOpen Access04 Oct 2022
Scientific Reports

Volume: 12, P: 1-15
TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury

Shubhayu Bhattacharyay
Florian D. van Leeuwen
Tommaso Zoerle
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-18
Polycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment

Nandini Singarapu
Keyue Ma
Ellen R. Richie
ResearchOpen Access25 Sept 2018
Scientific Reports

Volume: 8, P: 1-14
Correction to: Association of day-of-injury plasma glial fibrillary acidic protein concentration and six-month posttraumatic stress disorder in patients with mild traumatic brain injury

Jacqueline R. Kulbe
Sonia Jain
Ross Zafonte
Amendments and CorrectionsOpen Access30 Sept 2022
Neuropsychopharmacology

Volume: 47, P: 2332