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Showing 1–3 of 3 results
Advanced filters: Author: Nao Sankoda Clear advanced filters

  • How boundary regions form in the epithelia of tissues, for example, the squamous–columnar junction is unclear. Here, the authors identify the transcription factors Sox2 and Gata4 as specifying the transitional epithelium in the murine squamous–columnar junction region in the stomach epithelia.

    • Nao Sankoda
    • Wataru Tanabe
    • Yoshiya Kawaguchi
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Hirano et al. show that expression of the MYC family member Mycl in adult pancreatic islets can increase proliferation and expand the functional β-cell population, thereby improving glucose control.

    • Michitada Hirano
    • Yusei So
    • Yasuhiro Yamada
    Research
    Nature Metabolism
    Volume: 4, P: 254-268

  • Cellular reprogramming and cancer development share properties. Here, the authors examine the impact of in vivo reprogramming on Kras-induced cancer and show reprogramming-mediated repression of somatic cell enhancers in conjunction with Kras mutation results in rapid PDAC development.

    • Hirofumi Shibata
    • Shingo Komura
    • Yasuhiro Yamada
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16