Comprehensive investigation of proteome changes in old-age across mammalian tissues was missing. Here, the authors provide proteome and transcriptome data of major tissues of 6, 15, 24, and 30-month-old mice. Age-related post-transcriptional dysregulation most affects ECM and OXPHOS proteins.
- Masaki Takasugi
- Yoshiki Nonaka
- Naoko Ohtani