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Showing 1–2 of 2 results
Advanced filters: Author: Naomi Hoenisch Gravel Clear advanced filters

  • Here, Heitmann et al. report results from a Phase I/II trial evaluating CoVac-1, a peptide-based T-cell activator, in patients with B-cell deficiency, demonstrating potent induction of SARS-CoV-2-specific T-cell responses along with a favorable safety profile.

    • Jonas S. Heitmann
    • Claudia Tandler
    • Juliane S. Walz
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-10

  • MS-based immunopeptidomics provides direct evidence for HLA peptide-antigen presentation, which is indispensable for therapeutic use. Here the authors present an ion mobility MS-based immunopeptidome workflow, largely expand benign reference databases and enables next generation tumor antigen discovery.

    • Naomi Hoenisch Gravel
    • Annika Nelde
    • Juliane S. Walz
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-12