Nature Search

Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome

Here the authors use fast kinetics, X-ray crystallography, and cryo-EM to uncover the mechanism of ribosome inhibition by amikacin and kanamycin. They find that amikacin binds near the P-site tRNA, offering new strategies to fight antibiotic resistance.

Savannah M. Seely
Narayan P. Parajuli
Matthieu G. Gagnon
ResearchOpen Access03 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Structure–function comparison of Arbekacin with other aminoglycosides elucidates its higher potency as bacterial translation inhibitor

Soneya Majumdar
Narayan Prasad Parajuli
Suparna Sanyal
ResearchOpen Access25 May 2025
Scientific Reports

Volume: 15, P: 1-11
Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria

Thermorubin is a ribosome-targeting antibiotic. Here, using fast-kinetics and cryoEM, the authors reveal that thermorubin primarily blocks ribosome-recycling by tethering the ribosomal subunits besides impeding translation elongation and termination steps.

Narayan Prasad Parajuli
Andrew Emmerich
Suparna Sanyal
ResearchOpen Access17 Feb 2023
Nature Communications

Volume: 14, P: 1-14
Observation of quantum entanglement with top quarks at the ATLAS detector

Entanglement was observed in top–antitop quark events by the ATLAS experiment produced at the Large Hadron Collider at CERN using a proton–proton collision dataset with a centre-of-mass energy of √s = 13 TeV and an integrated luminosity of 140 fb⁻¹.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access18 Sept 2024
Nature

Volume: 633, P: 542-547
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Observation of electroweak production of two jets and a Z-boson pair

The ATLAS Collaboration reports the observation of the electroweak production of two jets and a Z-boson pair. This process is related to vector-boson scattering and allows the nature of electroweak symmetry breaking to be probed.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access09 Feb 2023
Nature Physics

Volume: 19, P: 237-253
Test of the universality of τ and μ lepton couplings in W-boson decays with the ATLAS detector

The ATLAS Collaboration reports a measurement of the ratio of the decay rates of W bosons to τ leptons and muons, in agreement with universal lepton couplings as postulated in the standard model of particle physics.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access05 Jul 2021
Nature Physics

Volume: 17, P: 813-818
Search for charged-lepton-flavour violation in Z-boson decays with the ATLAS detector

The ATLAS experiment at the Large Hadron Collider reports a search for charged-lepton-flavour violation in decays of Z bosons into a τ lepton and an electron or muon of opposite charge.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access01 Jul 2021
Nature Physics

Volume: 17, P: 819-825
A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

Ten years after the discovery of the Higgs boson, the ATLAS experiment at CERN probes its kinematic properties with a significantly larger dataset from 2015–2018 and provides further insights on its interaction with other known particles.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access04 Jul 2022
Nature

Volume: 607, P: 52-59
Micronutrients deficiencies and its correlation with the soil-transmitted helminthic infections among children and non-pregnant women in Nepal: findings from Nepal national micronutrient status survey

Suresh Mehata
Kedar Raj Parajuli
Dipendra Raman Singh
ResearchOpen Access24 Dec 2022
Scientific Reports

Volume: 12, P: 1-13
Serum zinc status is a matter of concern among children and non-pregnant women in a nationwide survey of Nepal

Suresh Mehata
Man Kumar Tamang
Dipendra Raman Singh
ResearchOpen Access21 Jul 2021
Scientific Reports

Volume: 11, P: 1-14
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5

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