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Showing 1–14 of 14 results
Advanced filters: Author: Natalia Dudareva Clear advanced filters

  • As Nature Chemical Biology approaches its third decade we asked a collection of chemical biologists, “What do you think are the most exciting frontiers or the most needed developments in your main field of research?” — here is what they said.

    • Lona M. Alkhalaf
    • Cheryl Arrowsmith
    • Georg Winter
    Special Features
    Nature Chemical Biology
    Volume: 21, P: 6-15

  • Bioactive sesquiterpenes accumulating in petunia stigmas are synthesized in the floral tube and then transported to the pistil via natural fumigation within the internal airspace of the developing flower.

    • Benoît Boachon
    • Joseph H. Lynch
    • Natalia Dudareva
    Research
    Nature Chemical Biology
    Volume: 15, P: 583-588

  • In addition to its incorporation into proteins, phenylalanine serves as an important precursor for natural products and components of the plant cell wall. The identification of the last gene in phenylalanine biosynthesis explains why flux in this pathway traffics through an arogenate intermediate in plants.

    • Hiroshi Maeda
    • Heejin Yoo
    • Natalia Dudareva
    Research
    Nature Chemical Biology
    Volume: 7, P: 19-21

  • Benzaldehyde is a simple aromatic aldehyde that attracts pollinators, has antifungal properties and contributes to flavor in many plants. Here the authors show that benzaldehyde is synthesized in petunia via the benzoic acid β-oxidative pathway by a peroxisomal heterodimeric enzyme consisting of α and β subunits.

    • Xing-Qi Huang
    • Renqiuguo Li
    • Natalia Dudareva
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15

  • The plant cuticle was initially thought to act as a passive diffusion barrier. Genetic and metabolic analysis reveals that it is also a sink/concentrator for volatiles protecting cells from toxic effects of these hydrophobic compounds.

    • Pan Liao
    • Shaunak Ray
    • Natalia Dudareva
    Research
    Nature Chemical Biology
    Volume: 17, P: 138-145

  • In plants, the cytosolic phenylalanine biosynthetic intermediate phenylpyruvate can serve as an amino acceptor in tryptophan-dependent auxin biosynthesis, thus facilitating crosstalk between these two distinct primary metabolic pathways.

    • Joseph H. Lynch
    • Yichun Qian
    • Natalia Dudareva
    Research
    Nature Chemical Biology
    Volume: 16, P: 850-856

  • Phenylalanine is mostly synthesized in plant plastids, but cytosolic transamination of phenylpyruvate also contributes. Here the authors show that a cytosolic chorismate mutase and a prephenate dehydratase encoded by an isoform of the plastidial ADT3 enzyme, produce phenylpyruvate in the cytosol.

    • Yichun Qian
    • Joseph H. Lynch
    • Natalia Dudareva
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-15

  • Phenylalanine is synthesized in plant chloroplasts and is then exported to the cytosol, where it is a precursor for various secondary metabolites. Here, the authors identify PhpCAT as a plastid phenylalanine transporter required to maintain metabolic flux in petunia.

    • Joshua R. Widhalm
    • Michael Gutensohn
    • Natalia Dudareva
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-11

  • Plants primarily synthesize phenylalanine in plastids via arogenate. Here, Yoo et al. provide evidence that petunia flowers also employ an alternative microbial-like pathway to synthesize phenylalanine that is partially localized in the cytosol and interconnected with tyrosine catabolism.

    • Heejin Yoo
    • Joshua R. Widhalm
    • Natalia Dudareva
    Research
    Nature Communications
    Volume: 4, P: 1-11

  • The origin and regulatory roles of isopentenyl phosphate (IP) in plant terpenoid metabolism remain unclear. Now, a study reports the enzymes for IP production and shows that these enzymes can be used to manipulate terpene production.

    • Laura K. Henry
    • Suzanne T. Thomas
    • Natalia Dudareva
    Research
    Nature Plants
    Volume: 4, P: 721-729

  • Two high-quality genomes of petunia wild parents reveal two rounds of hexaploidization in the evolution of Petunia lineage and provide insights into the diversity of floral patterns and pollination systems — enhancing the model value of this genus.

    • Aureliano Bombarely
    • Michel Moser
    • Cris Kuhlemeier
    ResearchOpen Access
    Nature Plants
    Volume: 2, P: 1-9

  • Decades of research have identified the biochemical basis of many plant specialized metabolic pathways. This Review highlights the biological context of these pathways and how recent advances have extended the new frontiers of phytochemistry.

    • Jing-Ke Weng
    • Joseph H. Lynch
    • Natalia Dudareva
    Reviews
    Nature Chemical Biology
    Volume: 17, P: 1037-1045